Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.42 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.37 |
| ▸ | FDPS | P14324 | 3/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972833 | 0.85 | PLA2G2C (0.48) | PLA2G2APLA2G2D | |
| SCHEMBL8973228 | 0.83 | LPAR5 (0.45) | LPAR3LPAR1LPAR2SGPL1PLA2G2A | |
| Dexfosfoserine SCHEMBL8973494 | 0.82 | S1PR1 (0.47) | — | |
| SCHEMBL8733089 | 0.82 | ASAH2 (0.43) | FDPS | |
| SCHEMBL8734261 | 0.82 | ASAH2 (0.43) | FDPS | |
| SCHEMBL8729196 | 0.82 | ASAH2 (0.43) | FDPS | |
| SCHEMBL8733300 | 0.79 | ASAH2 (0.43) | — | |
| SCHEMBL8731051 | 0.79 | ASAH2 (0.43) | — | |
| Phosphorylethanolamine SCHEMBL8973011 | 0.78 | LPAR3 (0.56) | LPAR3LPAR1LPAR2PLA2G2A | |
| SCHEMBL8972402 | 0.76 | PLA2G2A (0.43) | SGPL1FDPSPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701561-A1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | LABORATORIOS MENARINI S.A. (ES) | 1996-03-20 | — | — | EP | disclosed |
| WO-1994028004-A1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | LABORATORIOS MENARINI S.A. (ES) | 1994-12-08 | — | — | WO | disclosed |