SCHEMBL8733300

SCHEMBL8733300

CCCCCCCCCCS(=O)(=O)N[C@H](CO)CCCC

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ASAH2 Q9NR71 1/20 0.43
FAAH O00519 2/20 0.38
LMNA P02545 1/20 0.38
PLA2G2C Q5R387 1/20 0.37
RELA Q04206 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8731051 1.00 ASAH2 (0.43) ASAH2FAAHLMNAPLA2G2CRELA
SCHEMBL8733089 0.97 ASAH2 (0.43) ASAH2FAAHLMNA
SCHEMBL8729196 0.97 ASAH2 (0.43) ASAH2FAAHLMNA
SCHEMBL8734261 0.97 ASAH2 (0.43) ASAH2FAAHLMNA
SCHEMBL8727561 0.87 ASAH2 (0.40) ASAH2LMNA
SCHEMBL8734422 0.80 ASAH2 (0.43) ASAH2
Phosphorylethanolamine SCHEMBL8972363 0.79 LPAR3 (0.42)
SCHEMBL8733329 0.79 MEN1 (0.42)
SCHEMBL27884082 0.79 LMNA (0.45) LMNA
SCHEMBL27550371 0.78 ALDH1A1 (0.39) LMNAPLA2G2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0701561-B1 DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 MENARINI LAB (ES) 1998-08-19 EP disclosed
EP-0701561-A1 DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 LABORATORIOS MENARINI S.A. (ES) 1996-03-20 EP disclosed
WO-1994028004-A1 DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 LABORATORIOS MENARINI S.A. (ES) 1994-12-08 WO disclosed