Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331792 | 0.98 | ACHE (0.37) | ACHES1PR1S1PR2S1PR4S1PR3 | |
| Hydrochloric Acid SCHEMBL7335718 | 0.97 | ACHE (0.39) | ACHES1PR1S1PR2S1PR4S1PR3 | |
| Hydrochloric Acid SCHEMBL7344687 | 0.78 | — | — | |
| SCHEMBL21447846 | 0.74 | ACHE (0.44) | ACHES1PR1S1PR2S1PR4S1PR3 | |
| SCHEMBL8973657 | 0.71 | ESR1 (0.30) | — | |
| SCHEMBL332173 | 0.69 | ACHE (0.37) | ACHE | |
| SCHEMBL333101 | 0.69 | ESR1 (0.31) | — | |
| SCHEMBL1150855 | 0.69 | DRD2 (0.53) | ACHECYP11B1CYP11B2 | |
| SCHEMBL4666253 | 0.69 | DRD2 (0.53) | ACHECYP11B1CYP11B2 | |
| SCHEMBL17702023 | 0.69 | DRD2 (0.53) | ACHECYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486541-A | FOR TREATING PARKINSON*S DISEASE, MEMORY DISORDERS, ALZHEIMER*S DISEASE, DEPRESSION OR HYPERACTIVE SYNDROME | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1996-01-23 | — | — | US | disclosed |