Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | CDK9 | P50750 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11650361 | 0.81 | EPHX2 (0.61) | HSD17B10NAPRTEPHX1TP53TSHR | |
| SCHEMBL10457010 | 0.81 | EPHX2 (0.61) | HSD17B10NAPRTEPHX1TP53TSHR | |
| SCHEMBL3175598 | 0.79 | SMN1; SMN2 (0.58) | HSD17B10NAPRTEPHX1TP53TSHR | |
| SCHEMBL8392332 | 0.78 | NAPRT (0.54) | HSD17B10NAPRTEPHX1TP53TSHR | |
| SCHEMBL4589529 | 0.78 | MEN1 (0.56) | SMN1; SMN2GAAALDH1A1LMNAMAPT | |
| SCHEMBL5313666 | 0.77 | SMN1; SMN2 (0.56) | HSD17B10NAPRTEPHX1TP53TSHR | |
| SCHEMBL5681693 | 0.77 | EPHX2 (0.56) | HSD17B10NAPRTEPHX1TP53TSHR | |
| SCHEMBL9360689 | 0.77 | EPHX2 (0.56) | HSD17B10NAPRTEPHX1TP53TSHR | |
| SCHEMBL8393640 | 0.77 | SMN1; SMN2 (0.56) | HSD17B10NAPRTEPHX1TP53TSHR | |
| SCHEMBL8396654 | 0.77 | TP53 (0.56) | HSD17B10NAPRTEPHX1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | claimed |
| EP-1440976-B1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-07-23 | — | — | EP | claimed |
| US-20040214819-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2004-10-28 | — | — | US | claimed |
| EP-1440976-A1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-07-28 | — | — | EP | claimed |
| US-20030069231-A1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | RUDOLF KLAUS (DE) | 2003-04-10 | — | — | US | claimed |
| US-20010036946-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | RUDOLF KLAUS (DE) | 2001-11-01 | — | — | US | claimed |
| EP-0927192-A1 | MODIFIED AMINOACIDS, PHARMACEUTICALS CONTAINING THESE COMPOUNDS AND METHOD FOR THEIR PRODUCTION | Dr. Karl Thomae GmbH (DE) | 1999-07-07 | — | — | EP | claimed |
| WO-1998011128-A1 | MODIFIED AMINOACIDS, PHARMACEUTICALS CONTAINING THESE COMPOUNDS AND METHOD FOR THEIR PRODUCTION | DR. KARL THOMAE GMBH (DE) | 1998-03-19 | — | — | WO | claimed |
| US-20230142119-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-11 | — | — | US | disclosed |
| US-20220306578-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-09-29 | — | — | US | disclosed |
| US-11345914-B2 | Composition for delivering nucleic acid and nucleic acid-containing composition | TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES (JP) | 2022-05-31 | — | — | US | disclosed |
| CN-107249589-B | Physiologically active substance-binding block copolymer | 日本化药株式会社 | 2021-06-08 | — | — | CN | disclosed |
| US-20210115440-A1 | NUCLEIC ACID DELIVERY COMPOSITION, AND NUCLEIC ACID-CONTAINING COMPOSITION | TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES (JP) | 2021-04-22 | — | — | US | disclosed |
| EP-3263107-B1 | BLOCK COPOLYMER CONJUGATE OF PHYSIOLOGICALLY ACTIVE SUBSTANCE | NIPPON KAYAKU KK (JP) | 2020-11-11 | — | — | EP | disclosed |
| US-4075162-A | BICHROMOPHORIC BENZOXAZOLE-STYRENE ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS | EASTMAN KODAK COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-4073745-A | Multichromophoric benzotriazole ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
| US-4070337-A | Bichromophoric benzotriazole-styrene ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1978-01-24 | — | — | US | disclosed |
| US-4070339-A | Bichromophoric benzotriazole-styrene ester ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1978-01-24 | — | — | US | disclosed |
| US-4062800-A | Bichromophoric benzoxazole-styrene ester and amide ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1977-12-13 | — | — | US | disclosed |
| US-3981884-A | POLYMERS | EASTMAN KODAK COMPANY (US) | 1976-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142119-A1 | TETRACYCLIC COMPOUND | ALK, TTR, ACVR1 | HSD17B10 2091/4885NAPRT 1804/4885EPHX1 2261/4885 |
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, CHRM1, SRMS | HSD17B10 4618/4885NAPRT 4093/4885EPHX1 2612/4885 |
| US-20220306578-A1 | TETRACYCLIC COMPOUND | ALK, TTR, ACVR1 | HSD17B10 2091/4885NAPRT 1804/4885EPHX1 2261/4885 |
| US-20040214819-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, SRMS, OPRM1 | HSD17B10 4236/4885NAPRT 4191/4885EPHX1 2441/4885 |
| US-20030069231-A1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | SLC1A5, NEFM, SRMS | HSD17B10 3992/4885NAPRT 4232/4885EPHX1 2183/4885 |
| US-20010036946-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, SRMS, OPRM1 | HSD17B10 4236/4885NAPRT 4191/4885EPHX1 2441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.