Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 16/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708779 | 0.98 | KIF11 (0.69) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL22150730 | 0.97 | KIF11 (0.71) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL28515838 | 0.87 | KIF11 (0.66) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL5058831 | 0.87 | KIF11 (0.66) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL9172236 | 0.85 | KIF11 (0.57) | KIF11KCNH2 | |
| SCHEMBL29060869 | 0.84 | KIF11 (0.88) | KIF11KCNH2SMN1; SMN2 | |
| SCHEMBL9395267 | 0.84 | KIF11 (0.62) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL19809495 | 0.84 | KIF11 (0.62) | KIF11KCNH2HTT | |
| SCHEMBL7453762 | 0.83 | KIF11 (0.59) | KIF11KCNH2 | |
| SCHEMBL8724574 | 0.82 | KIF11 (0.61) | KIF11KCNH2LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416817-B1 | Amplification processes | ZENECA LTD (GB) | 1996-10-16 | — | — | EP | disclosed |
| US-5525494-A | Amplification processes | ZENECA LIMITED (GB) | 1996-06-11 | — | — | US | disclosed |
| EP-0416817-A2 | Amplification processes | ZENECA LIMITED (GB) | 1991-03-13 | — | — | EP | disclosed |