Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 16/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708779 | 0.98 | KIF11 (0.69) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL8972758 | 0.97 | KIF11 (0.68) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL5058831 | 0.90 | KIF11 (0.66) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL28515838 | 0.90 | KIF11 (0.66) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL7706703 | 0.85 | KIF11 (0.73) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL10877618 | 0.85 | KIF11 (0.73) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL6551716 | 0.84 | KIF11 (0.61) | KIF11KCNH2 | |
| SCHEMBL15212059 | 0.83 | KIF11 (0.71) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL7708780 | 0.83 | KIF11 (0.66) | KIF11KCNH2HTT | |
| SCHEMBL7826138 | 0.83 | KIF11 (0.57) | KIF11KCNH2LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3674407-A1 | MODIFIED POLYNUCLEOTIDE | National University Corporation Nagoya University (JP) | 2020-07-01 | — | — | EP | disclosed |