Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 16/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972758 | 0.98 | KIF11 (0.68) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL22150730 | 0.98 | KIF11 (0.71) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL5058831 | 0.88 | KIF11 (0.66) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL28515838 | 0.88 | KIF11 (0.66) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL7453762 | 0.84 | KIF11 (0.59) | KIF11KCNH2 | |
| SCHEMBL7706703 | 0.83 | KIF11 (0.73) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL10877618 | 0.83 | KIF11 (0.73) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL29060869 | 0.83 | KIF11 (0.88) | KIF11KCNH2SMN1; SMN2 | |
| SCHEMBL9172236 | 0.82 | KIF11 (0.57) | KIF11KCNH2 | |
| SCHEMBL6551716 | 0.82 | KIF11 (0.61) | KIF11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208234-A1 | POLY(ETHER-THIOETHER), POLY(ETHER-SULFOXIDE) AND POLY(ETHER-SULFONE) NUCLEIC ACIDS | BIO-RAD LABORATORIES, INC. (US) | 2002-05-29 | — | — | EP | disclosed |
| US-6348583-B1 | NUCLEOBASE CONTAINING POLYTHIOETHERS SYNTHESIZED ON POLYETHYLENE GLYCOL, SUCCINIC ANHYDRIDE AND PROPYLAMINE MODIFIED GLASS; NUCLEIC ACID MIMETICS | BIO-RAD LABORATORIES, INC. | 2002-02-19 | — | — | US | disclosed |
| WO-2001016365-A1 | POLY(ETHER-THIOETHER), POLY(ETHER-SULFOXIDE) AND POLY(ETHER-SULFONE) NUCLEIC ACIDS | BIO-RAD LABORATORIES, INC. (US) | 2001-03-08 | — | — | WO | disclosed |