Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.59 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.59 |
| ▸ | BAX | Q07812 | 1/20 | 0.59 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.57 |
| ▸ | ESR1 | P03372 | 5/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069693 | 0.96 | CYP3A4 (0.54) | LTA4HNR1H2BAXHSD17B1HSD17B2 | |
| SCHEMBL37670120 | 0.94 | LTA4H (0.67) | LTA4HNR1H2BAXHSD17B1HSD17B2 | |
| SCHEMBL70648 | 0.94 | LTA4H (0.67) | LTA4HNR1H2BAXHSD17B1HSD17B2 | |
| SCHEMBL28419866 | 0.94 | LTA4H (0.67) | LTA4HNR1H2BAXHSD17B1HSD17B2 | |
| SCHEMBL2906301 | 0.92 | LTA4H (0.64) | LTA4HNR1H2BAXHSD17B1HSD17B2 | |
| SCHEMBL9292956 | 0.91 | HSD17B1 (0.68) | LTA4HNR1H2BAXHSD17B1HSD17B2 | |
| SCHEMBL21311883 | 0.90 | HSD17B1 (0.67) | LTA4HNR1H2BAXHSD17B1HSD17B2 | |
| SCHEMBL5027612 | 0.89 | LTA4H (0.58) | LTA4HNR1H2BAXESR1ESR2 | |
| SCHEMBL29458645 | 0.89 | LTA4H (0.58) | LTA4HNR1H2BAXESR1ESR2 | |
| SCHEMBL8076305 | 0.89 | LTA4H (0.58) | LTA4HNR1H2BAXESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699216-A1 | MELT PROCESSABLE POLYESTERS AND POLY(IMIDE-ESTERS) | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-03-06 | — | — | EP | claimed |
| WO-1994028052-A1 | MELT PROCESSABLE POLYESTERS AND POLY(IMIDE-ESTERS) | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-12-08 | — | — | WO | claimed |