Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 10/20 | 0.68 |
| ▸ | HSD17B2 | P37059 | 10/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.61 |
| ▸ | ESR1 | P03372 | 4/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | BAX | Q07812 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 2/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.53 |
| ▸ | BCR | P11274 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21311926 | 0.96 | HSD17B1 (0.61) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL4674827 | 0.94 | HSD17B1 (0.76) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL21311877 | 0.94 | ESR1 (0.61) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL27090262 | 0.94 | ESR1 (0.61) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL21311883 | 0.93 | HSD17B1 (0.67) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL8972767 | 0.91 | LTA4H (0.59) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL27090234 | 0.91 | LTA4H (0.64) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL4677364 | 0.91 | HSD17B1 (0.74) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL19542210 | 0.89 | HSD17B1 (0.65) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL7035776 | 0.89 | LTA4H (0.69) | HSD17B1HSD17B2ESR1ESR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288835-A | 4,4*-bis(hydroxyphenoxy)biphenyl as one of the monomer | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-02-22 | — | — | US | claimed |