Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 9/20 | 0.71 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.71 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973477 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL31632756 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL4548016 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL8972731 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL8972071 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL8972364 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL8972105 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL8973186 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL3339374 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL4548026 | 0.98 | L3MBTL1 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268222-B1 | Penetration enhancers for transdermal delivery of systemic agents | RES TRIANGLE PHARM LTD (US) | 1996-03-27 | — | — | EP | disclosed |
| EP-0582065-A1 | 1-Oxohydrocarbyl-substituted azacyclohexanes compositions used as acid catalyst | WHITBY RESEARCH, Inc. (US) | 1994-02-09 | — | — | EP | disclosed |
| EP-0280703-B1 | COMPOSITIONS COMPRISING 1-ACYL-SUBSTITUTED MORPHOLINES, THIOMORPHOLINES AND PIPERAZINES AND THEIR USES | WHITBY RESEARCH INC (US) | 1993-12-29 | — | — | EP | disclosed |
| US-5073544-A | Penetration promoters | WHITBY, INC. (US) | 1991-12-17 | — | — | US | disclosed |
| US-4917896-A | PIPERAZINE, MORPHOLINE OR THIOMORPHOLINE DERIVATIVE | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1990-04-17 | — | — | US | disclosed |
| EP-0268222-A2 | Penetration enhancers for transdermal delivery of systemic agents | RESEARCH TRIANGLE PHARMACEUTICALS LTD. (US) | 1988-05-25 | — | — | EP | disclosed |