Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 9/20 | 0.71 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.71 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973477 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL8972731 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL8972105 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL8973186 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL31632756 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL8972364 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL4548016 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL8972852 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL8972071 | 1.00 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL4548026 | 0.98 | L3MBTL1 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144708-A1 | HETEROCYCLIC COMPOUNDS CONTAINING NITROGEN ATOMS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME FOR TREATMENT OF CANCER | KOREA RESEARCH INSTITITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144708-A1 | HETEROCYCLIC COMPOUNDS CONTAINING NITROGEN ATOMS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME FOR TREATMENT OF CANCER | RHOT2, BAX, BCL2 | GNAI3 413/4885GNAI1 320/4885GNAO1 924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.