SCHEMBL8972892

SCHEMBL8972892

CC1(c2ccccc2Oc2cccc(N)c2)CCC(C(C)(C)c2ccc(Oc3cccc(N)c3)cc2)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.41
ALDH1A1 P00352 6/20 0.37
ATM Q13315 1/20 0.34
MAPT P10636 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MITF O75030 1/20 0.33
GFER P55789 1/20 0.33
NLRP1 Q9C000 1/20 0.33
NOD2 Q9HC29 1/20 0.33
DDB1 Q16531 1/20 0.33
CRBN Q96SW2 1/20 0.33
LTA4H P09960 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
NCOA1 Q15788 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8973157 0.90 ALDH1A1 (0.41) ALDH1A1MAPTSMN1; SMN2GAAMEN1
SCHEMBL8539436 0.72 KDM1A (0.41) MAOBALDH1A1ATMMAPTSMN1; SMN2
SCHEMBL8202665 0.69 NCOA1 (0.44) ALDH1A1MAPTSMN1; SMN2GAAMEN1
SCHEMBL6289225 0.69 MAOB (0.77) MAOBALDH1A1ATMMAPTSMN1; SMN2
SCHEMBL6293868 0.69 MAOB (0.77) MAOBALDH1A1ATMMAPTSMN1; SMN2
SCHEMBL6289841 0.69 MAOB (0.77) MAOBALDH1A1ATMMAPTSMN1; SMN2
SCHEMBL6290521 0.69 MAOB (0.77) MAOBALDH1A1ATMMAPTSMN1; SMN2
SCHEMBL6290463 0.69 MAOB (0.77) MAOBALDH1A1ATMMAPTSMN1; SMN2
SCHEMBL1269982 0.69 MAOB (0.77) MAOBALDH1A1ATMMAPTSMN1; SMN2
SCHEMBL6293115 0.69 MAOB (0.77) MAOBALDH1A1ATMMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0710690-A2 Polyimide film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-05-08 EP disclosed
US-5498687-A Unsaturated imide compounds containing alicyclic structure, process for producing the same and intermediate therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-03-12 US disclosed
US-5489669-A FORMED FROM AMINE CONTAINING BIS/4-AMINOPHENOXY/PHENYL GROUPS; SOLUBILITY, DIELECTRICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-06 US disclosed
US-5444165-A Reacting diamino compound with unsaturated dicarboxylic anhydride to form amic acid intermediate, catalytic dehydration-ring closing; solvent soluble, low water absorption and flexibility SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-08-22 US disclosed
EP-0633282-A1 Polyimide and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-11 EP disclosed
US-5326881-A Polymers with good heat resistance, good flexibility and low water absorption SUMITOMO CHEMICAL COMPANY LTD. (JP) 1994-07-05 US disclosed
EP-0595230-A1 Unsaturated imide compounds containing alicyclic structure SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-05-04 EP disclosed