SCHEMBL8973157

SCHEMBL8973157

CC1(c2ccccc2Oc2ccc(N)cc2)CCC(C(C)(C)c2ccc(Oc3ccc(N)cc3)cc2)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.41
MAPT P10636 4/20 0.41
RAB9A P51151 4/20 0.41
NPC1 O15118 3/20 0.41
HPGD P15428 1/20 0.41
MAPK1 P28482 1/20 0.41
NCOA1 Q15788 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41
MAOA P21397 1/20 0.36
TDP1 Q9NUW8 2/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
TEAD4 Q15561 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
NLRP3 Q96P20 1/20 0.31
SMN1; SMN2 Q16637 3/20 0.31
POLB P06746 2/20 0.31
MITF O75030 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8972892 0.90 MAOB (0.41) ALDH1A1MAPTRAB9ANPC1HPGD
SCHEMBL8990291 0.79 ALDH1A1 (0.33) ALDH1A1MAPTRAB9ANPC1HPGD
SCHEMBL8202665 0.78 NCOA1 (0.44) ALDH1A1MAPTRAB9ANPC1HPGD
SCHEMBL8468197 0.77 NCOA1 (0.47) ALDH1A1MAPTRAB9ANPC1HPGD
SCHEMBL23037320 0.72 GAA (0.34) ALDH1A1HPGDKMT2AGAA
SCHEMBL23037322 0.72 GAA (0.34) ALDH1A1HPGDKMT2AGAA
SCHEMBL8698973 0.69 KDM1A (0.42) ALDH1A1MAPTRAB9ANPC1HPGD
SCHEMBL1851070 0.68 ALDH1A1 (0.58) ALDH1A1MAPTRAB9ANPC1HPGD
SCHEMBL3095989 0.66 NCOA1 (0.46) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL1851072 0.66 ALDH1A1 (0.56) ALDH1A1MAPTRAB9ANPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5498687-A Unsaturated imide compounds containing alicyclic structure, process for producing the same and intermediate therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-03-12 US disclosed
US-5489669-A FORMED FROM AMINE CONTAINING BIS/4-AMINOPHENOXY/PHENYL GROUPS; SOLUBILITY, DIELECTRICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-06 US disclosed
US-5444165-A Reacting diamino compound with unsaturated dicarboxylic anhydride to form amic acid intermediate, catalytic dehydration-ring closing; solvent soluble, low water absorption and flexibility SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-08-22 US disclosed
EP-0633282-A1 Polyimide and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-11 EP disclosed
US-5326881-A Polymers with good heat resistance, good flexibility and low water absorption SUMITOMO CHEMICAL COMPANY LTD. (JP) 1994-07-05 US disclosed
EP-0595230-A1 Unsaturated imide compounds containing alicyclic structure SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-05-04 EP disclosed