Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | RRM1 | P23921 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533283 | 0.88 | AKR1C2 (0.45) | MTNR1ARRM1L3MBTL1NR4A2MEN1 | |
| SCHEMBL8533289 | 0.88 | AKR1C2 (0.45) | MTNR1ARRM1L3MBTL1NR4A2MEN1 | |
| SCHEMBL10552187 | 0.82 | NR4A2 (0.41) | MTNR1ABACE1NR4A2AKR1C2PLAU | |
| SCHEMBL10552181 | 0.82 | NR4A2 (0.41) | MTNR1ABACE1NR4A2AKR1C2PLAU | |
| SCHEMBL1668640 | 0.79 | NR4A2 (0.54) | MTNR1AABCG2L3MBTL1NR4A2MEN1 | |
| SCHEMBL9152862 | 0.77 | NPC1 (0.41) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL8200612 | 0.77 | NPC1 (0.41) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL8200609 | 0.77 | NPC1 (0.41) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL23712595 | 0.76 | ALDH1A1 (0.39) | NR4A2MEN1KMT2AKDM4EGAA | |
| SCHEMBL8533287 | 0.76 | MEN1 (0.43) | MTNR1AL3MBTL1NR4A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566455-B1 | Derivatives of 7-ethynyle alpha-(methoxymethylene)1-naphthalenacetic acid, their process of preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1996-03-06 | — | — | EP | claimed |
| US-5451696-A | Parasiticide intermediate | ROUSSEL-UCLAF (FR) | 1995-09-19 | — | — | US | claimed |
| JP-6025095-A | — | — | None | — | — | JP | disclosed |
| JP-H0625095-A | NEW DERIVATIVE OF 7-ETHYNYL-ALPHA-(METHOXYMETHYLENE)-1-NAPHTHALENE ACETIC ACID, ITS PREPARATION AND ITS USE AS AGENT FOR EXTERMINATING PEST | ROUSSEL UCLAF | 1994-02-01 | — | — | JP | disclosed |