SCHEMBL10552181

SCHEMBL10552181

CO/C=C(/C(=O)OC)c1cccc2ccc(-c3ccccc3)cc12

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MTNR1A P48039 2/20 0.40
AKR1C2 P52895 1/20 0.40
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
BACE1 P56817 1/20 0.38
PLAU P00749 2/20 0.38
DHODH Q02127 1/20 0.38
MTNR1B P49286 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10552187 1.00 NR4A2 (0.41) NR4A2ALDH1A1HPGDSMN1; SMN2MTNR1A
SCHEMBL8972901 0.82 MTNR1A (0.42) NR4A2ALDH1A1HPGDSMN1; SMN2MTNR1A
SCHEMBL9550507 0.79 ERAP1 (0.47) ALDH1A1HPGDSMN1; SMN2
SCHEMBL23987343 0.78 NR4A2 (0.40) NR4A2ALDH1A1HPGDDHODH
SCHEMBL9550421 0.78 ERAP1 (0.41) ALDH1A1HPGDDHODH
SCHEMBL8949021 0.77 NR4A2 (0.43) NR4A2ALDH1A1HPGDSMN1; SMN2MTNR1A
SCHEMBL8949014 0.77 NR4A2 (0.43) NR4A2ALDH1A1HPGDSMN1; SMN2MTNR1A
SCHEMBL8949018 0.77 NR4A2 (0.43) NR4A2ALDH1A1HPGDSMN1; SMN2MTNR1A
SCHEMBL9214778 0.76 NR4A2 (0.44) NR4A2ALDH1A1HPGDSMN1; SMN2MTNR1A
SCHEMBL9550484 0.76 MAOA (0.47) ALDH1A1HPGDBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337672-A1 METHOD OF CONTROLLING SOYBEAN RUST FUNGUS HAVING RESISTANCE TO QoI FUNGICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-10-26 US disclosed
US-4877811-A FUNGICIDES, INSECTICIDES, MITICIDES, PLANTH GROWTH REGULATORS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-10-31 US disclosed
EP-0267734-A2 Chemical compounds ZENECA LIMITED (GB) 1988-05-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337672-A1 METHOD OF CONTROLLING SOYBEAN RUST FUNGUS HAVING RESISTANCE TO QoI FUNGICIDE CYC1, SQOR, MT-CO1 NR4A2 2627/4885ALDH1A1 4422/4885HPGD 3137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.