SCHEMBL8972975

SCHEMBL8972975

CC(=O)Nc1ccc(N=Nc2c(S(=O)(=O)O)cc3cc(N)ccc3c2O)c(S(=O)(=O)O)c1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.61
EP300 Q09472 1/20 0.61
PRMT6 Q96LA8 1/20 0.61
PRMT1 Q99873 1/20 0.61
CD40 P25942 1/20 0.60
CD40LG P29965 1/20 0.60
PHLPP2 Q6ZVD8 1/20 0.53
ENPP2 Q13822 12/20 0.51
CA2 P00918 1/20 0.51
CA3 P07451 1/20 0.51
AMY1A P0DUB6 1/20 0.41
CASP6 P55212 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8779865 0.90 PRMT3 (0.64) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL13959636 0.89 PRMT1 (0.50) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL9137047 0.89 PRMT3 (0.65) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL10350700 0.88 PRMT3 (0.61) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL10350701 0.88 PRMT3 (0.61) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL10600174 0.86 PHLPP2 (0.60) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL13959649 0.84 PRMT1 (0.55) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL12511368 0.83 PRMT3 (0.51) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL8779952 0.81 CD40 (0.56) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL7770984 0.81 PHLPP2 (0.62) PRMT1CD40CD40LGPHLPP2ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4772323-A IMPROVED STORAGE AND EJECTION STABILITY CANON KABUSHIKI KAISHA (JP) 1988-09-20 US claimed
EP-0481449-B1 Ink compositions for ink jet recording SUMITOMO CHEMICAL CO (JP) 1996-03-27 EP disclosed
US-5183501-A A water-soluble azo, phthalocyanine, anthraquinone, dioxazine or formazan dye having one or more-SO2-CH2-CH2-SO3H groups, a solvent and water; heat and water resistance; colorfastness SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-02-02 US disclosed
EP-0481449-A2 Ink compositions for ink jet recording SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-04-22 EP disclosed
EP-0219232-B1 WATER-SOLUBLE DYE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-08-29 EP disclosed
EP-0167219-B1 FIBER-REACTIVE COMPOUND HAVING BOTH PYRIDINIOTRIAZINYL AND VINYLSULFONE TYPE GROUPS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-09-28 EP disclosed
US-4772323-A IMPROVED STORAGE AND EJECTION STABILITY CANON KABUSHIKI KAISHA (JP) 1988-09-20 US disclosed
US-4758658-A Water-soluble formazan dye IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-07-19 US disclosed
EP-0219232-A2 Water-soluble dye IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-04-22 EP disclosed
US-4626589-A Organic dye compound having both pyridiniotriazinyl and vinylsulfone type fiber-reactive groups SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-12-02 US disclosed
EP-0167219-A1 Fiber-reactive compound having both pyridiniotriazinyl and vinylsulfone type groups SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-01-08 EP disclosed
EP-0059355-A2 Use of reactive dyestuffs in dyeing and printing of hydroxylgroups containing fibrous materials BAYER AG (DE) 1982-09-08 EP disclosed
US-4263206-A Reactive dyestuffs containing chlorine or fluorine substituents and one or more 1,3-dicyanobenzene radicals linked to the dyestuff at the 2-, 4- or 6-position IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-04-21 US disclosed
US-4213899-A FOR CELLULOSE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-07-22 US disclosed