SCHEMBL8779952

SCHEMBL8779952

NC(=O)Nc1ccc2c(O)c(N=Nc3cc(N)ccc3S(=O)(=O)O)c(S(=O)(=O)O)cc2c1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CD40 P25942 1/20 0.56
CD40LG P29965 1/20 0.56
PRMT3 O60678 1/20 0.52
EP300 Q09472 1/20 0.52
PRMT6 Q96LA8 1/20 0.52
PRMT1 Q99873 1/20 0.52
ENPP2 Q13822 10/20 0.51
PHLPP2 Q6ZVD8 1/20 0.47
NT5E P21589 1/20 0.45
CASP6 P55212 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
CA2 P00918 1/20 0.43
CA3 P07451 1/20 0.43
MEN1 O00255 1/20 0.41
THRB P10828 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8779865 0.91 PRMT3 (0.64) CD40CD40LGPRMT3EP300PRMT6
SCHEMBL8035550 0.87 PHLPP2 (0.57) CD40CD40LGPRMT3EP300PRMT6
SCHEMBL11423898 0.85 ENPP2 (0.62) CD40CD40LGPRMT3EP300PRMT6
SCHEMBL10351775 0.85 MEN1 (0.56) CD40CD40LGPRMT1ENPP2PHLPP2
SCHEMBL10588141 0.81 ENPP2 (0.49) CD40CD40LGPRMT1ENPP2PHLPP2
SCHEMBL8972975 0.81 PRMT3 (0.61) CD40CD40LGPRMT3EP300PRMT6
SCHEMBL7770978 0.81 PHLPP2 (0.54) CD40CD40LGPRMT1ENPP2PHLPP2
SCHEMBL8070763 0.81 PHLPP2 (0.54) CD40CD40LGPRMT1ENPP2PHLPP2
SCHEMBL7766620 0.78 PHLPP2 (0.61) CD40CD40LGPRMT3EP300PRMT6
SCHEMBL7591259 0.78 PHLPP2 (0.61) CD40CD40LGPRMT3EP300PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0492128-B1 Triazine compounds and method for dyeing or printing fiber materials using the same SUMITOMO CHEMICAL CO (JP) 1997-06-04 EP disclosed
EP-0481449-B1 Ink compositions for ink jet recording SUMITOMO CHEMICAL CO (JP) 1996-03-27 EP disclosed
US-5235046-A Colorfast, washfast SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-10 US disclosed
US-5183501-A A water-soluble azo, phthalocyanine, anthraquinone, dioxazine or formazan dye having one or more-SO2-CH2-CH2-SO3H groups, a solvent and water; heat and water resistance; colorfastness SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-02-02 US disclosed
EP-0492128-A1 Triazine compounds and method for dyeing or printing fiber materials using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-07-01 EP disclosed
EP-0481449-A2 Ink compositions for ink jet recording SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-04-22 EP disclosed
US-4263206-A Reactive dyestuffs containing chlorine or fluorine substituents and one or more 1,3-dicyanobenzene radicals linked to the dyestuff at the 2-, 4- or 6-position IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-04-21 US disclosed