SCHEMBL8972989

SCHEMBL8972989

C=CCCCCCCCCCCc1ccc(C(=O)O)cc1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.57
ALDH1A1 P00352 2/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
RARA P10276 1/20 0.57
MAPT P10636 1/20 0.57
MTOR P42345 1/20 0.57
THRA P10827 4/20 0.51
THRB P10828 4/20 0.51
ATG4B Q9Y4P1 7/20 0.49
PLA2G1B P04054 6/20 0.49
CYP1A2 P05177 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
RECQL P46063 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3096780 1.00 RARB (0.57) RARBALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL3107799 1.00 RARB (0.57) RARBALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL3108533 1.00 RARB (0.57) RARBALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL3111116 1.00 RARB (0.57) RARBALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL3107771 0.98 ALDH1A1 (0.58) RARBALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL8611134 0.95 RARB (0.65) RARBALDH1A1MEN1KMT2AL3MBTL1
Hydrochloric Acid SCHEMBL8612294 0.94 RARB (0.63) RARBALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL3100075 0.93 ALDH1A1 (0.60) RARBALDH1A1MEN1KMT2AL3MBTL1
Biphenyl SCHEMBL9304661 0.91 RARB (0.56) RARBALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL14386726 0.86 THRA (0.51) MEN1KMT2ATHRATHRBATG4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545409-B1 Liquid crystals with end groups containing more than one silane group CONSORTIUM ELEKTROCHEM IND (DE) 1996-03-06 EP disclosed
US-5399290-A Liquid crystals with (polysila) alkyl wing groups CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1995-03-21 US disclosed
EP-0545409-A1 Liquid crystals with end groups containing more than one silane group Consortium für elektrochemische Industrie GmbH (DE) 1993-06-09 EP disclosed