SCHEMBL8973177

SCHEMBL8973177

COC(=O)c1ccc(OCCCCOc2ccc(OC)cc2)cc1C(=O)OC

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
MAPT P10636 4/20 0.51
MTNR1A P48039 1/20 0.50
MTNR1B P49286 1/20 0.50
PLA2G2A P14555 2/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
HPGD P15428 1/20 0.47
RAB9A P51151 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
POLB P06746 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8588735 0.92 MAOB (0.53) KDM4ECYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL7157499 0.89 MAPT (0.60) KDM4ECYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL8085882 0.88 MAOA (0.60) PLA2G2AMAOAMAOB
SCHEMBL27098581 0.88 MAPT (0.47) KDM4ECYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL21543811 0.87 MAOA (0.55) KDM4ECYP1A2CYP2C19MAPTPLA2G2A
SCHEMBL11454639 0.86 MAPT (0.60) KDM4ECYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL16836640 0.86 MAOA (0.62) MAOAMAOB
SCHEMBL24830103 0.85 MAPT (0.49) MAPTMAOAMAOBRAB9AL3MBTL1
SCHEMBL7161239 0.84 MAPT (0.67) KDM4ECYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL18199320 0.84 PLA2G2A (0.50) KDM4EMAPTPLA2G2AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0538751-B1 Thermal transfer image-receiving material FUJI PHOTO FILM CO LTD (JP) 1996-03-06 EP disclosed
US-5326740-A Image storage stability, antifading group incorporated in the polyester layer FUJI PHOTO FILM CO., LTD. (JP) 1994-07-05 US disclosed
EP-0538751-A1 Thermal transfer image-receiving material FUJI PHOTO FILM CO., LTD. (JP) 1993-04-28 EP disclosed