Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085882 | 0.97 | MAOA (0.60) | MAOAMAOBPLA2G2APTPN11TSHR | |
| SCHEMBL16836640 | 0.95 | MAOA (0.62) | MAOAMAOBPTPN11TSHRTHRA | |
| SCHEMBL18199320 | 0.93 | PLA2G2A (0.50) | MAOAMAOBL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL20129246 | 0.93 | RARB (0.54) | MAOAMAOBL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL28279461 | 0.92 | PTPN11 (0.56) | MAOAMAOBL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8588735 | 0.92 | MAOB (0.53) | MAOAMAOBL3MBTL1KDM4EMAPT | |
| SCHEMBL16482859 | 0.89 | MAOA (0.54) | MAOAMAOBL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL28870271 | 0.88 | PTPN11 (0.62) | MAOAMAOBPLA2G2APTPN11TSHR | |
| SCHEMBL28280526 | 0.88 | PTPN11 (0.62) | MAOAMAOBPLA2G2APTPN11TSHR | |
| SCHEMBL27098563 | 0.88 | MAPT (0.49) | MAOAMAOBL3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021455-B2 | Brominated furanone derivative, method for preparing same, and pharmaceutical composition containing same as active ingredient | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2021-06-01 | — | — | US | disclosed |
| US-20190345126-A1 | NOVEL BROMINATED FURANONE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2019-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021455-B2 | Brominated furanone derivative, method for preparing same, and pharmaceutical composition containing same as active ingredient | TAS2R20, BLVRB, FDPS | MAOA 3108/4885MAOB 2995/4885L3MBTL1 4833/4885 |
| US-20190345126-A1 | NOVEL BROMINATED FURANONE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | TAS2R20, BLVRB, NOTUM | MAOA 2994/4885MAOB 2972/4885L3MBTL1 4842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.