Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9092992 | 0.83 | GABRA1 (0.51) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL4985552 | 0.78 | TRPA1 (0.41) | MAOBTRPA1MAPK1L3MBTL1MAPT | |
| SCHEMBL2414269 | 0.78 | CYP1A2 (0.51) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31235495 | 0.78 | CYP1A2 (0.51) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9155382 | 0.77 | MAPK1 (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Methane SCHEMBL27317936 | 0.76 | CYP1A2 (0.50) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL25612575 | 0.76 | USP2 (0.58) | L3MBTL1MAPTTSHR | |
| SCHEMBL12780420 | 0.75 | MAOB (0.51) | MAOBTRPA1MAPK1L3MBTL1MAPT | |
| SCHEMBL769167 | 0.75 | MAPK1 (0.65) | MAOBTRPA1MAPK1L3MBTL1 | |
| SCHEMBL31368564 | 0.75 | MAPK1 (0.65) | MAOBTRPA1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534635-A | Process for preparing pyridine-2-carboxamides | HOFFMANN-LA ROCHE INC. (US) | 1996-07-09 | — | — | US | disclosed |
| US-5380861-A | Process for preparing pyridine 2-carboxamides | HOFFMANN-LA ROCHE INC. (US) | 1995-01-10 | — | — | US | disclosed |