Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.35 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3196146 | 0.80 | KMT2A (0.60) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL173014 | 0.76 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL18627019 | 0.76 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL29517618 | 0.76 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL13893056 | 0.76 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL9732046 | 0.76 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL5644348 | 0.76 | ALOX5 (0.32) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL9711964 | 0.76 | LMNA (0.48) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL9711982 | 0.76 | LMNA (0.48) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL18685585 | 0.76 | APOBEC3G (0.41) | LMNAKMT2AMEN1BLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1113361-A | — | — | None | — | — | JP | disclosed |
| US-5493057-A | INTERMEDIATES FOR REACTIVE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-20 | — | — | US | disclosed |
| JP-H01113361-A | OXYETHYL MERCAPTO-BENZALDEHYDE AND PREPARATION OF OXIDATION PRODUCT OF THE SAME | HOECHST AG | 1989-05-02 | — | — | JP | disclosed |