Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29517618 | 1.00 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL16935337 | 0.98 | LMNA (0.52) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL6536177 | 0.83 | LMNA (0.46) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL3196146 | 0.80 | KMT2A (0.60) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL20005510 | 0.79 | CDK4 (0.52) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL986274 | 0.79 | ERN1 (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL4800076 | 0.78 | ALOX5 (0.43) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL9732046 | 0.76 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL5950805 | 0.76 | ALOX5 (0.42) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL8973253 | 0.76 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 453 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110713447-B | Preparation method of p-methylthio benzaldehyde | 山东国邦药业有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-110143971-B | Methylthiophenyl substituted chromone structure-containing spiro [ indazole-isoxazole ] derivative, and preparation method and application thereof | 绍兴文理学院 | 2021-04-30 | — | — | CN | claimed |
| CN-111395694-A | Mould proof heat conduction floor based on graphite alkene | 安徽扬子地板股份有限公司 | 2020-07-10 | — | — | CN | claimed |
| CN-110713447-A | Preparation method of p-methylthio benzaldehyde | 山东国邦药业有限公司 | 2020-01-21 | — | — | CN | claimed |
| CN-107827791-B | A kind of synthetic method of stable isotope labeling Thiamphenicol | 山东辉璟生物医药科技有限公司 | 2019-09-24 | — | — | CN | claimed |
| US-20030232994-A1 | Bicyclic thiophene derivatives and combinatorial libraries thereof | LION BIOSCIENCE AG (DE) | 2003-12-18 | — | — | US | claimed |
| EP-0702008-B1 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS (JP) | 2001-08-29 | — | — | EP | claimed |
| EP-0572712-B1 | Processes for producing 2-substituted benzo(beta)thiophene | SUMITOMO SEIKA CHEMICALS (JP) | 1998-01-21 | — | — | EP | claimed |
| EP-0702008-A2 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-03-20 | — | — | EP | claimed |
| US-5298630-A | Reacting 2-alkylthiobenzaldehyde derivative with halo compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1994-03-29 | — | — | US | claimed |
| EP-0572712-A2 | Processes for producing 2-substituted benzo(beta)thiophene | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1993-12-08 | — | — | EP | claimed |
| JP-5331134-A | — | — | None | — | — | JP | disclosed |
| JP-6087852-A | — | — | None | — | — | JP | disclosed |
| JP-5331162-A | — | — | None | — | — | JP | disclosed |
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | FUJIFILM CORPORATION (JP) | 2025-10-23 | — | — | US | disclosed |
| US-3959474-A | 2,6-Diamino-1,4-dihydropyridine-3,5-dicarboxylic acid esters used as coronary vessel dilators and anti-hypertensive agents | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | disclosed |
| US-3957998-A | ADMINISTERING | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
| US-3951993-A | HYPOTENSIVE, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3950336-A | HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |
| US-3933834-A | CARDIOVASCULAR AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232994-A1 | Bicyclic thiophene derivatives and combinatorial libraries thereof | CXCR2, BICRA, CXCR1 | LMNA 4767/4885KMT2A 3575/4885MEN1 2243/4885 |
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | ABCB11, ABCC1, SLC11A2 | LMNA 4425/4885KMT2A 1705/4885MEN1 3362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.