SCHEMBL8973309

SCHEMBL8973309

CCCOC(=O)c1sccc1S(=O)(=O)N=C=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.38
STS P08842 1/20 0.36
ESR1 P03372 1/20 0.36
CHRM1 P11229 1/20 0.36
TSHR P16473 1/20 0.36
SLC6A2 P23975 1/20 0.36
KDR P35968 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PKM P14618 1/20 0.35
MAPK14 Q16539 1/20 0.35
NPC1 O15118 2/20 0.34
MAPT P10636 2/20 0.34
RAB9A P51151 2/20 0.34
TP53 P04637 2/20 0.34
SREBF1 P36956 1/20 0.34
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
KMT2A Q03164 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9147014 0.90 ALDH1A1 (0.41) LMNAALDH1A1HPGDPKMNPC1
SCHEMBL6228599 0.82 EDNRA (0.46) LMNAALDH1A1HPGDTSHRNPC1
SCHEMBL8973493 0.80 STS (0.47) LMNAALDH1A1HPGDSTSESR1
SCHEMBL8973162 0.80 ALDH1A1 (0.42) LMNAALDH1A1HPGDSTSESR1
Hydrochloric Acid SCHEMBL9148624 0.79 STS (0.46) LMNAALDH1A1HPGDSTSESR1
SCHEMBL11111735 0.76 ALDH1A1 (0.58) LMNAALDH1A1STSTSHRTDP1
SCHEMBL7031237 0.76 MAPT (0.35) LMNAALDH1A1HPGDSTSESR1
SCHEMBL7034620 0.76 MAPT (0.38) LMNAALDH1A1HPGDSTSESR1
SCHEMBL7030558 0.76 CA12 (0.35) LMNAALDH1A1HPGDSTSESR1
SCHEMBL7031465 0.76 ALDH1A1 (0.34) LMNAALDH1A1HPGDSTSESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5508441-A Herbicidal substituted thienylsulphonylureas BAYER AKTIENGESELLSCHAFT (DE) 1996-04-16 US disclosed
US-5430006-A Herbicidal substituted thienylsulphonylureas BAYER AKTIENGESELLSCHAFT (DE) 1995-07-04 US disclosed
EP-0590416-A1 Substituted sulfonylureas as herbizides BAYER AG (DE) 1994-04-06 EP disclosed