Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | EDNRA | P25101 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973307 | 0.88 | PKM (0.45) | ALDH1A1LMNAHPGDTSHRMAPT | |
| SCHEMBL8973493 | 0.85 | STS (0.47) | ALDH1A1LMNAHPGDESR1CHRM1 | |
| Hydrochloric Acid SCHEMBL9148624 | 0.84 | STS (0.46) | ALDH1A1LMNAHPGDESR1CHRM1 | |
| SCHEMBL8973309 | 0.80 | LMNA (0.38) | ALDH1A1LMNAHPGDESR1CHRM1 | |
| SCHEMBL388034 | 0.80 | MAPT (0.55) | LMNAHPGDTSHRMAPTTP53 | |
| SCHEMBL10941833 | 0.78 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDESR1CHRM1 | |
| SCHEMBL9729949 | 0.78 | CYP3A4 (0.44) | ALDH1A1LMNAHPGDTSHRTDP1 | |
| SCHEMBL8973501 | 0.75 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDESR1CHRM1 | |
| SCHEMBL27923752 | 0.74 | PKM (0.46) | ALDH1A1LMNAHPGDTSHRMAPT | |
| SCHEMBL4095819 | 0.73 | LMNA (0.44) | ALDH1A1LMNAHPGDTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508441-A | Herbicidal substituted thienylsulphonylureas | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |
| US-5430006-A | Herbicidal substituted thienylsulphonylureas | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-04 | — | — | US | disclosed |
| EP-0590416-A1 | Substituted sulfonylureas as herbizides | BAYER AG (DE) | 1994-04-06 | — | — | EP | disclosed |