Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | EDNRA | P25101 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973309 | 0.90 | LMNA (0.38) | ALDH1A1PKMKMT2AMAPTRAB9A | |
| SCHEMBL6228599 | 0.85 | EDNRA (0.46) | ALDH1A1KMT2AMAPTNPC1HPGD | |
| SCHEMBL27923752 | 0.80 | PKM (0.46) | ALDH1A1PKMKMT2AMAPTRAB9A | |
| SCHEMBL8973307 | 0.79 | PKM (0.45) | ALDH1A1PKMKMT2AMAPTRAB9A | |
| SCHEMBL8973588 | 0.79 | PKM (0.45) | ALDH1A1PKMKMT2AMAPTRAB9A | |
| SCHEMBL7030744 | 0.76 | MAPT (0.39) | ALDH1A1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL9188413 | 0.75 | TSHR (0.56) | ALDH1A1KMT2AMAPTNPC1HPGD | |
| SCHEMBL30806173 | 0.75 | TSHR (0.56) | ALDH1A1KMT2AMAPTNPC1HPGD | |
| SCHEMBL7034917 | 0.75 | MAPT (0.46) | ALDH1A1MAPTRAB9AHPGDKDM4E | |
| SCHEMBL7034553 | 0.75 | MAPT (0.39) | ALDH1A1MAPTSMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430006-A | Herbicidal substituted thienylsulphonylureas | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-04 | — | — | US | disclosed |
| EP-0590416-A1 | Substituted sulfonylureas as herbizides | BAYER AG (DE) | 1994-04-06 | — | — | EP | disclosed |