Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 8/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 8/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31474905 | 0.84 | CES2 (0.30) | CES2LPAR1LPAR3 | |
| SCHEMBL15431935 | 0.80 | — | — | |
| SCHEMBL11522292 | 0.79 | — | — | |
| SCHEMBL11519475 | 0.79 | — | — | |
| SCHEMBL31236108 | 0.78 | — | — | |
| SCHEMBL17136266 | 0.75 | TSHR (0.35) | TSHRLMNACES2LPAR1LPAR3 | |
| SCHEMBL1221382 | 0.75 | TSHR (0.35) | TSHRLMNACES2LPAR1LPAR3 | |
| SCHEMBL798836 | 0.75 | TSHR (0.35) | TSHRLMNACES2LPAR1LPAR3 | |
| SCHEMBL10339095 | 0.75 | CES2 (0.41) | TSHRCES2LPAR1LPAR3FAAH | |
| SCHEMBL60281 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485479-B1 | PERFLUORO-T-BUTYL-CONTAINING COMPOUNDS FOR USE IN FLUORINE-19 NMR AND/OR MRI | UNIV JOHNS HOPKINS (US) | 1996-04-03 | — | — | EP | disclosed |
| US-5397563-A | Perfluoro-t-butyl-containing steroids for use in fluorine-19 NMR and/or MRI | THE JOHNS HOPKINS UNIVERSITY (US) | 1995-03-14 | — | — | US | disclosed |
| US-5324504-A | Nine magnetically equivalent fluorine nuclei generate a single intense resonance for detection | THE JOHNS HOPKINS UNIVERSITY (US) | 1994-06-28 | — | — | US | disclosed |
| US-5234680-A | Generates single, intense resonance for easy detection in imaging or spectroscopy | JOHNS HOPKINS UNIV. (US) | 1993-08-10 | — | — | US | disclosed |
| US-5116599-A | Imaging compounds for medical diagnosis | JOHNS HOPKINS UNIV. (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0485479-A1 | PERFLUORO-T-BUTYL-CONTAINING COMPOUNDS FOR USE IN FLUORINE-19 NMR AND/OR MRI. | UNIV JOHNS HOPKINS (US) | 1992-05-20 | — | — | EP | disclosed |
| WO-1991001759-A1 | PERFLUORO-T-BUTYL-CONTAINING COMPOUNDS FOR USE IN FLUORINE-19 NMR AND/OR MRI | THE JOHNS HOPKINS UNIVERSITY (US) | 1991-02-21 | — | — | WO | disclosed |