Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.51 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973340 | 0.91 | PRMT1 (0.56) | PRMT1WDR5NQO2ALDH1A1TOP1 | |
| SCHEMBL8975569 | 0.89 | PRMT1 (0.63) | PRMT1WDR5NQO2NPC1ALDH1A1 | |
| SCHEMBL8975885 | 0.88 | PRMT1 (0.46) | PRMT1WDR5NQO2NPC1RAB9A | |
| SCHEMBL8975918 | 0.85 | PRMT1 (0.41) | PRMT1WDR5NQO2NPC1RAB9A | |
| SCHEMBL8975727 | 0.84 | RXFP1 (0.44) | PRMT1WDR5NQO2NPC1RAB9A | |
| SCHEMBL14155330 | 0.84 | PRMT1 (0.48) | PRMT1WDR5NQO2NPC1RAB9A | |
| SCHEMBL14369783 | 0.83 | WDR5 (0.47) | PRMT1WDR5NQO2NPC1ALDH1A1 | |
| SCHEMBL8975609 | 0.80 | RXFP1 (0.49) | PRMT1WDR5NQO2NPC1ALDH1A1 | |
| SCHEMBL8975490 | 0.80 | PRMT1 (0.52) | PRMT1WDR5NQO2NPC1RAB9A | |
| SCHEMBL8975458 | 0.80 | PRMT1 (0.44) | PRMT1WDR5NQO2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188121-B2 | Substituted pyridines as antiparasitic AZA teraryl compounds | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-05-29 | — | — | US | disclosed |
| US-20110257199-A1 | NOVEL TERARYL COMPOUNDS AS ANTIPARASITIC AGENTS | TIDWELL RICHARD R | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257199-A1 | NOVEL TERARYL COMPOUNDS AS ANTIPARASITIC AGENTS | DDT, ZC3HAV1, MAVS | PRMT1 2522/4885WDR5 1227/4885NQO2 2186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.