Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R46 | P59540 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL585278 | 0.95 | TAS2R46 (0.38) | TAS2R46MEN1KMT2ARECQLTDP1 | |
| SCHEMBL585277 | 0.95 | TAS2R46 (0.38) | TAS2R46MEN1KMT2ARECQLTDP1 | |
| SCHEMBL1153227 | 0.95 | TAS2R46 (0.38) | TAS2R46MEN1KMT2ARECQLTDP1 | |
| SCHEMBL17627758 | 0.95 | TAS2R46 (0.38) | TAS2R46MEN1KMT2ARECQLTDP1 | |
| SCHEMBL3504653 | 0.95 | TAS2R46 (0.38) | TAS2R46MEN1KMT2ARECQLTDP1 | |
| SCHEMBL21004881 | 0.84 | TAS2R46 (0.32) | TAS2R46MEN1KMT2ARECQLTDP1 | |
| SCHEMBL21004882 | 0.84 | TAS2R46 (0.32) | TAS2R46MEN1KMT2ARECQLTDP1 | |
| SCHEMBL2575638 | 0.80 | LMNA (0.35) | TAS2R46MEN1KMT2ARECQLTDP1 | |
| SCHEMBL2575636 | 0.80 | LMNA (0.35) | TAS2R46MEN1KMT2ARECQLTDP1 | |
| SCHEMBL16236106 | 0.78 | TAS2R46 (0.35) | TAS2R46MEN1KMT2ARECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440362-B1 | 2,2-Dimethyl-1-nitrilo or 2,2-dimethyl-1-hydroxylamino-3-(alkyl phenyl)substituted propanes or 2-methyl-1-nitrilo-or 2-methyl-1-hydroxylamino-3-(methoxyphenyl) propane, organoleptic uses thereof and processes for preparing same | INT FLAVORS & FRAGRANCES INC (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0531636-B1 | Process for preparing phenyl butyronitriles and perfumery use of 2,2-dimethyl-4-phenyl valeronitrile | INT FLAVORS & FRAGRANCES INC (US) | 1995-10-18 | — | — | EP | disclosed |
| EP-0347596-B1 | Bleaching composition | INT FLAVORS & FRAGRANCES INC (US) | 1995-07-12 | — | — | EP | disclosed |
| EP-0383446-B1 | 2,4,4-Trisubstituted tetrahydropyranyl esters and organoleptic uses thereof | INT FLAVORS & FRAGRANCES INC (US) | 1995-05-03 | — | — | EP | disclosed |
| US-5236897-A | Reacting isobutyronitrile with 2- or 4-vinyl pyridine; augments and enhances aromas | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0531636-A1 | Process for preparing phenyl butyronitriles and perfumery use of 2,2-dimethyl-4-phenyl valeronitrile | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5179222-A | Reaction of isobutyronitrile with styrene derivatives in the presence of sodium hydride and lithium diisopropylamide | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1993-01-12 | — | — | US | disclosed |
| US-5143899-A | Process for preparing phenyl butyronitriles and perfumery use of 2,2-dimethyl-4-phenyl valeronitrile | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0440362-A1 | 2,2-Dimethyl-1-nitrilo or 2,2-dimethyl-1-hydroxylamino-3-(alkyl phenyl)substituted propanes or 2-methyl-1-nitrilo-or 2-methyl-1-hydroxylamino-3-(methoxyphenyl) propane, organoleptic uses thereof and processes for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1991-08-07 | — | — | EP | disclosed |
| US-4990494-A | 1,1-dimethyl-1-nitrilo or hydroxylamino-3-(alkyl phenyl)-substituted propanes, organoleptic uses thereof and processes for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1991-02-05 | — | — | US | disclosed |
| EP-0383446-A2 | 2,4,4-Trisubstituted tetrahydropyranyl esters and organoleptic uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1990-08-22 | — | — | EP | disclosed |
| EP-0347596-A2 | Bleaching composition | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1989-12-27 | — | — | EP | disclosed |
| US-4863631-A | Dimethyl substituted alkyl nitriles, perfume and bleach compositions containing same organoleptic uses thereof and process intermediates for producing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4822515-A | Ethyl norbornyl alkyl ethers, organoleptic uses thereof and process for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1989-04-18 | — | — | US | disclosed |
| US-4772411-A | ETHYL TRICYCLOHEPTYL ALKYL ETHERS, BLEACHES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0042734-B1 | OLEFIN DIMERS, DERIVATIVES THEREOF AND ORGANOLEPTIC USES THEREOF | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1985-03-20 | — | — | EP | disclosed |
| US-4390448-A | Perfumed stable aqueous hypochlorite bleach compositions containing 2-methyl-2-octanol and thickened variation thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1983-06-28 | — | — | US | disclosed |
| US-4342663-A | Use of mixture of aliphatic C10 branched olefins in augmenting or enhancing the aroma of articles subjected to action of aqueous hypochlorites | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 1982-08-03 | — | — | US | disclosed |
| US-4330425-A | Use of mixture of aliphatic C10 branched olefin epoxides in augmenting or enhancing the aroma of articles subjected to action of aqueous hypochlorites | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1982-05-18 | — | — | US | disclosed |
| EP-0042734-A2 | Olefin dimers, derivatives thereof and organoleptic uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-12-30 | — | — | EP | disclosed |