SCHEMBL2575636

SCHEMBL2575636

CC(=O)C1CC/C(C)=C\CC/C=C(/C)C/C=C/1C

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.35
CYP3A4 P08684 2/20 0.34
ALOX15 P16050 2/20 0.34
TAS2R46 P59540 4/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
RECQL P46063 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TERT O14746 1/20 0.33
PKM P14618 1/20 0.33
PTPN1 P18031 1/20 0.32
MET P08581 1/20 0.31
CNR2 P34972 1/20 0.30
PPARA Q07869 1/20 0.30
MAPK1 P28482 1/20 0.30
CHRNA7 P36544 1/20 0.30
STAT3 P40763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2575638 1.00 LMNA (0.35) LMNACYP3A4ALOX15TAS2R46MEN1
SCHEMBL28556508 0.88 TAS2R46 (0.33) LMNACYP3A4ALOX15TAS2R46MEN1
SCHEMBL585277 0.82 TAS2R46 (0.38) LMNACYP3A4ALOX15TAS2R46MEN1
SCHEMBL3504653 0.82 TAS2R46 (0.38) LMNACYP3A4ALOX15TAS2R46MEN1
SCHEMBL1153227 0.82 TAS2R46 (0.38) LMNACYP3A4ALOX15TAS2R46MEN1
SCHEMBL17627758 0.82 TAS2R46 (0.38) LMNACYP3A4ALOX15TAS2R46MEN1
SCHEMBL585278 0.82 TAS2R46 (0.38) LMNACYP3A4ALOX15TAS2R46MEN1
SCHEMBL8973506 0.80 TAS2R46 (0.35) LMNATAS2R46MEN1KMT2ARECQL
SCHEMBL22442455 0.75 MEN1 (0.44) LMNATAS2R46MEN1KMT2ARECQL
SCHEMBL22442456 0.75 MEN1 (0.44) LMNATAS2R46MEN1KMT2ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1072673-A2 Perfume compositions THE PROCTER & GAMBLE COMPANY (US) 2001-01-31 EP claimed
WO-2001005919-A2 PERFUME COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2001-01-25 WO claimed
EP-3096839-B1 SCENTED BODY COMPOSITIONS MAORI S C LTD (IL) 2021-08-11 EP disclosed
US-9943469-B2 Scented body compositions MAORI S.C. LTD. (IL) 2018-04-17 US disclosed
EP-2734178-B1 PERFUME COTY INC (US) 2018-01-17 EP disclosed
EP-2758027-B1 PERFUME COTY INC (US) 2017-10-25 EP disclosed
US-20160338915-A1 SCENTED BODY COMPOSITIONS AMKIRI LTD (IL) 2016-11-24 US disclosed
US-9109187-B2 Oud odorants FIRMENICH SA (CH) 2015-08-18 US disclosed
US-9102898-B2 Perfume COTY INC. (US) 2015-08-11 US disclosed
EP-2751238-B1 OUD ODORANTS FIRMENICH & CIE (CH) 2015-06-17 EP disclosed
US-20140371121-A1 OUD ODORANTS FIRMENICH SA (CH) 2014-12-18 US disclosed
US-20140128311-A1 PERFUME COTY INC. (US) 2014-05-08 US disclosed
US-20130023592-A1 PERFUME COTY INC. (US) 2013-01-24 US disclosed
EP-2181690-B1 Perfume composition with reduced alcohol content COTY INC (US) 2011-11-09 EP disclosed
US-7737107-B2 Trimethylcyclododecatriene derivatives, use thereof and perfumed products containing the same Fils, V. Mane (FR) 2010-06-15 US disclosed
EP-2181690-A1 Perfume composition with reduced alcohol content Coty Inc. (US) 2010-05-05 EP disclosed
US-20080139446-A1 Novel Trimethylcyclodoecatriene Derivatives, Use Thereof And Perfumed Products Containing The Same V. MANE FILS (FR) 2008-06-12 US disclosed
EP-1707185-A1 Solvent materials and methods for preparing fragrance compositions INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) 2006-10-04 EP disclosed
EP-1072673-A2 Perfume compositions THE PROCTER & GAMBLE COMPANY (US) 2001-01-31 EP disclosed
WO-2001005919-A2 PERFUME COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2001-01-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130023592-A1 PERFUME PLK3, PLK4, SMURF1 LMNA 2644/4885CYP3A4 1348/4885ALOX15 277/4885
US-20080139446-A1 Novel Trimethylcyclodoecatriene Derivatives, Use Thereof And Perfumed Products Containing The Same CBR3, C5, OXER1 LMNA 3511/4885CYP3A4 182/4885ALOX15 477/4885
US-20140371121-A1 OUD ODORANTS OPRD1, OR10J3, DRD4 LMNA 3939/4885CYP3A4 194/4885ALOX15 257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.