Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 4/20 | 0.60 |
| ▸ | APP | P05067 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TXN | P10599 | 1/20 | 0.49 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.48 |
| ▸ | STK17B | O94768 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973147 | 0.87 | NFKB1 (0.62) | NFKB1APPNPC1RAB9AMEN1 | |
| SCHEMBL8973728 | 0.83 | NFKB1 (0.57) | NFKB1APPNPC1MEN1KMT2A | |
| SCHEMBL11877727 | 0.83 | MEN1 (0.53) | NFKB1APPNPC1RAB9AMEN1 | |
| SCHEMBL5033983 | 0.83 | APP (0.60) | NFKB1APPNPC1RAB9AMEN1 | |
| SCHEMBL30345300 | 0.79 | NFKB1 (0.57) | NFKB1APPNPC1RAB9AMEN1 | |
| SCHEMBL14268288 | 0.79 | NFKB1 (0.57) | NFKB1APPNPC1MEN1KMT2A | |
| SCHEMBL19284139 | 0.79 | NFKB1 (0.57) | NFKB1APPNPC1RAB9AMEN1 | |
| SCHEMBL4838360 | 0.79 | NFKB1 (0.52) | NFKB1APPNPC1MEN1KMT2A | |
| SCHEMBL1392126 | 0.79 | APP (0.77) | NFKB1APPMEN1KMT2ARAPGEF4 | |
| SCHEMBL9513146 | 0.78 | RAPGEF4 (0.68) | NPC1RAB9AMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561131-A | INCREASING THE WOOL GROWTH BY ADMINISTERING AN ANTIPROTOZOA AGENT TO SHEEP | MALLINCKRODT VETERINARY, INC. (US) | 1996-10-01 | — | — | US | claimed |
| EP-0661976-A1 | DEFAUNATION METHOD | MALLINCKRODT VETERINARY LIMITED (AU) | 1995-07-12 | — | — | EP | claimed |
| EP-0661976-A4 | DEFAUNATION METHOD. | MALLINCKRODT VETERINARY LTD (AU) | 1994-07-20 | — | — | EP | claimed |
| WO-1993002680-A1 | DEFAUNATION METHOD | PITMAN-MOORE AUSTRALIA LIMITED (AU) | 1993-02-18 | — | — | WO | claimed |
| US-5561131-A | INCREASING THE WOOL GROWTH BY ADMINISTERING AN ANTIPROTOZOA AGENT TO SHEEP | MALLINCKRODT VETERINARY, INC. (US) | 1996-10-01 | — | — | US | disclosed |
| EP-0661976-A1 | DEFAUNATION METHOD | MALLINCKRODT VETERINARY LIMITED (AU) | 1995-07-12 | — | — | EP | disclosed |
| EP-0661976-A4 | DEFAUNATION METHOD. | MALLINCKRODT VETERINARY LTD (AU) | 1994-07-20 | — | — | EP | disclosed |
| WO-1993002680-A1 | DEFAUNATION METHOD | PITMAN-MOORE AUSTRALIA LIMITED (AU) | 1993-02-18 | — | — | WO | disclosed |