SCHEMBL8973627

SCHEMBL8973627

O=C(OCCOc1ccccc1)C(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 4/20 0.53
CHRM3 P20309 4/20 0.53
CHRM2 P08172 3/20 0.53
CHRM4 P08173 3/20 0.53
ALDH1A1 P00352 4/20 0.51
KMT2A Q03164 2/20 0.51
THRB P10828 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
TSHR P16473 1/20 0.49
PKM P14618 1/20 0.47
LMNA P02545 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
HPGD P15428 1/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3276207 0.90 CHRM3 (0.63) CHRM1CHRM3CHRM2CHRM4ALDH1A1
SCHEMBL1395611 0.83 ESR1 (0.62) CHRM1CHRM3CHRM2CHRM4ALDH1A1
SCHEMBL1395561 0.78 L3MBTL1 (0.49) CHRM1CHRM3CHRM2CHRM4ALDH1A1
SCHEMBL160688 0.78 ESR1 (0.69) CHRM1ALDH1A1KMT2ATHRBSMN1; SMN2
SCHEMBL8911681 0.77 DRD4 (0.69) ALDH1A1RAB9APKMLMNACYP1A2
SCHEMBL28713490 0.77 LMNA (0.56) CHRM1CHRM3CHRM2CHRM4ALDH1A1
SCHEMBL1395609 0.77 LMNA (0.59) CHRM1CHRM3CHRM2CHRM4ALDH1A1
SCHEMBL13516691 0.76 THRB (0.59) ALDH1A1KMT2ATHRBSMN1; SMN2NPC1
SCHEMBL13516692 0.76 THRB (0.59) ALDH1A1KMT2ATHRBSMN1; SMN2NPC1
SCHEMBL8752319 0.76 DRD3 (0.50) ALDH1A1KMT2APKMLMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5565306-A SUBSTRATE HAVING RECORDING LAYER CONTAINING PYRAZOLONE DERIVATIVE, HYDROQUINONE DERIVATIVE, ACIDIC SUBSTANCE MUTUALLY DISSOLVED THEREIN NEW OJI PAPER CO., LTD. (JP) 1996-10-15 US disclosed
EP-0424914-B1 Recording material NEW OJI PAPER CO LTD (JP) 1996-09-25 EP disclosed
EP-0403833-B1 Recording material NEW OJI PAPER CO LTD (JP) 1995-09-27 EP disclosed
EP-0665462-A1 Thermofixable photosensitive recording material and process for preparing thereof NEW OJI PAPER CO., LTD. (JP) 1995-08-02 EP disclosed
US-5372917-A Excellent color forming property, storage stability and recorded image preservability; pyrazolone derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-12-13 US disclosed
EP-0468459-B1 Heat-sensitive recording material KANZAKI PAPER MFG CO LTD (JP) 1994-02-16 EP disclosed
EP-0482668-B1 HEAT SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1993-08-04 EP disclosed
US-5212145-A Containing an ethyleneimine derivative as a preservability improving agent for record images KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-05-18 US disclosed
US-5206210-A Alpha naphthoic acid, storage stability KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-04-27 US disclosed
US-5187143-A Thermographic mixture of basic leuco dye and color developer comprising a zinc salt of terephthaldehydic acid or a composite salt also containing an aromatic acid KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-02-16 US disclosed
EP-0482668-A1 Heat sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1992-04-29 EP disclosed
US-5096872-A Colorless basic dye reacts with salicylic acid derivative to form colored image, paper KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1992-03-17 US disclosed
US-5094999-A Salicylic acid derivative KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1992-03-10 US disclosed
EP-0468459-A1 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1992-01-29 EP disclosed
EP-0424914-A2 Recording material NEW OJI PAPER CO., LTD. (JP) 1991-05-02 EP disclosed
EP-0403833-A2 Recording material NEW OJI PAPER CO., LTD. (JP) 1990-12-27 EP disclosed
US-4847236-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-07-11 US disclosed
EP-0272099-A2 Color-forming sheet recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-06-22 EP disclosed