Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837274 | 0.81 | TSHR (0.80) | TSHRMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL9484073 | 0.79 | GAA (0.46) | KMT2AP2RX7MEN1GAAPOLB | |
| SCHEMBL4544859 | 0.79 | KCNH3 (0.51) | MAPTKMT2AKDM4EALDH1A1NFKB1 | |
| Dyrene SCHEMBL7532886 | 0.79 | TSHR (0.83) | TSHRMAPTKMT2AKDM4EALDH1A1 | |
| Dyrene SCHEMBL9328304 | 0.79 | TSHR (0.75) | TSHRMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL4544870 | 0.79 | TSHR (0.51) | TSHRALDH1A1P2RX7MAPK1GAA | |
| Dyrene SCHEMBL16113661 | 0.78 | TSHR (0.80) | TSHRMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL1548694 | 0.77 | ALDH1A1 (0.54) | MAPTKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10939229 | 0.77 | TSHR (0.67) | TSHRMAPTKMT2AKDM4EALDH1A1 | |
| Dyrene SCHEMBL13280 | 0.76 | TSHR (1.00) | TSHRMAPTKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561131-A | INCREASING THE WOOL GROWTH BY ADMINISTERING AN ANTIPROTOZOA AGENT TO SHEEP | MALLINCKRODT VETERINARY, INC. (US) | 1996-10-01 | — | — | US | disclosed |
| EP-0661976-A1 | DEFAUNATION METHOD | MALLINCKRODT VETERINARY LIMITED (AU) | 1995-07-12 | — | — | EP | disclosed |
| EP-0661976-A4 | DEFAUNATION METHOD. | MALLINCKRODT VETERINARY LTD (AU) | 1994-07-20 | — | — | EP | disclosed |
| WO-1993002680-A1 | DEFAUNATION METHOD | PITMAN-MOORE AUSTRALIA LIMITED (AU) | 1993-02-18 | — | — | WO | disclosed |
| US-3931165-A | INSECTICIDES, HERBICIDES | BARER SOL J | 1976-01-06 | — | — | US | disclosed |