Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581544 | 0.81 | ATM (0.49) | L3MBTL1MAPTATMHPGDMEN1 | |
| SCHEMBL27655777 | 0.81 | L3MBTL1 (0.58) | L3MBTL1MAPTNPSR1PTPN1ATM | |
| SCHEMBL13791138 | 0.80 | PTPN1 (0.44) | L3MBTL1MAPTNPSR1PTPN1ATM | |
| SCHEMBL11941063 | 0.79 | CNR1 (0.51) | L3MBTL1MAPTNPSR1ATMHPGD | |
| SCHEMBL12454829 | 0.78 | CYP1A2 (0.50) | PTPN1MEN1KMT2AHTR1BCYP2A6 | |
| SCHEMBL8974681 | 0.77 | KDM4E (0.39) | L3MBTL1MAPTNPSR1PTPN1ATM | |
| SCHEMBL485405 | 0.76 | KCNN4 (0.40) | L3MBTL1PTPN1HPGDKDM4EHTR1B | |
| SCHEMBL8974913 | 0.76 | PTPN1 (0.37) | L3MBTL1MAPTPTPN1HPGDMEN1 | |
| SCHEMBL10434845 | 0.76 | PTPN1 (0.38) | L3MBTL1MAPTNPSR1PTPN1ATM | |
| SCHEMBL11941064 | 0.76 | CNR1 (0.53) | L3MBTL1MAPTNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7306898-B2 | Planographic printing method and planographic printing plate precursor used therein | FUJIFILM CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| US-5527948-A | SUBSTITUTED NAPHTHYL-ALKENOIC ACIDS FOR TREATING AUTOIMMUNE DISORDERS | EISAI CORP. LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| CN-1027064-C | Naphthalene derivatives | EISAI CO LTD (JP) | 1994-12-21 | — | — | CN | disclosed |
| US-5298649-A | Antiinflammatory agents, rheumatic agents and treatment of autoimmune diseases | EISAI CO., LTD. (JP) | 1994-03-29 | — | — | US | disclosed |
| EP-0376288-B1 | Naphthalene derivative | EISAI CO LTD (JP) | 1994-03-09 | — | — | EP | disclosed |
| US-5134111-A | Inhibitors of interleukin-1 as antiinflammatory agents | EISAI CO., LTD. (JP) | 1992-07-28 | — | — | US | disclosed |
| CN-1043696-A | NAPHTHALENE DERIVATIVES | EISAI CO LTD (JP) | 1990-07-11 | — | — | CN | disclosed |
| EP-0376288-A1 | Naphthalene derivative | Eisai Co., Ltd. (JP) | 1990-07-04 | — | — | EP | disclosed |