Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283334 | 0.90 | PTPN1 (0.40) | PTPN1GABRA1ALOX5PTGS2EGFR | |
| SCHEMBL12855014 | 0.87 | PTPN1 (0.41) | PTPN1GABRA1GABRB2MAPTL3MBTL1 | |
| SCHEMBL9901198 | 0.85 | PTPN1 (0.37) | PTPN1L3MBTL1ALOX5PTGS2EGFR | |
| SCHEMBL16958706 | 0.85 | L3MBTL1 (0.44) | MAPTL3MBTL1NPSR1KDM4EHPGD | |
| SCHEMBL16956545 | 0.84 | L3MBTL1 (0.49) | GABRA1GABRB2MAPTL3MBTL1NPSR1 | |
| SCHEMBL27655748 | 0.83 | L3MBTL1 (0.38) | PTPN1MAPTL3MBTL1NPSR1ALOX5 | |
| SCHEMBL9901394 | 0.83 | PTPN1 (0.38) | PTPN1ALOX5PTGS2EGFRKDM4E | |
| SCHEMBL16954472 | 0.82 | ALOX5 (0.45) | GABRA1GABRB2MAPTL3MBTL1ALOX5 | |
| SCHEMBL16962845 | 0.81 | MAPT (0.42) | MAPTL3MBTL1NPSR1HPGDATM | |
| SCHEMBL2048597 | 0.80 | EGFR (0.41) | PTPN1MAPTL3MBTL1NPSR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375368-A2 | Alcohol and ether derivatives | ZENECA LIMITED (GB) | 1990-06-27 | — | — | EP | disclosed |