Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973975 | 1.00 | GRM4 (0.31) | GRM4ALDH1A1NPC1GRM5RAB9A | |
| SCHEMBL8973721 | 0.76 | SLC10A1 (0.37) | ALDH1A1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL19514915 | 0.76 | HSD11B1 (0.37) | GRM4ALDH1A1NPC1GRM5RAB9A | |
| SCHEMBL19514968 | 0.75 | KMT2A (0.39) | ALDH1A1NPC1GRM5RAB9ASMN1; SMN2 | |
| SCHEMBL19514967 | 0.75 | KMT2A (0.39) | ALDH1A1NPC1GRM5RAB9ASMN1; SMN2 | |
| SCHEMBL19538278 | 0.68 | LCK (0.37) | NPC1RAB9AHDAC6MEN1KMT2A | |
| SCHEMBL8973919 | 0.68 | KCNH2 (0.35) | MEN1KMT2AKCNN4 | |
| SCHEMBL19514892 | 0.67 | GRM4 (0.55) | GRM4ALDH1A1NPC1GRM5RAB9A | |
| SCHEMBL19533138 | 0.67 | ALDH1A1 (0.55) | GRM4ALDH1A1NPC1GRM5RAB9A | |
| SCHEMBL7427498 | 0.67 | NFE2L2 (0.45) | GRM4ALDH1A1NPC1GRM5RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5548077-A | REACTING WITH CARBOHYDRATE COMPOUND TO FORM SCHIFF BASE, REDUCING SCHIFF BASE | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-08-20 | — | — | US | disclosed |
| US-5386033-A | 2-aminopyridine compounds | SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) (JP) | 1995-01-31 | — | — | US | disclosed |