SCHEMBL8974435

SCHEMBL8974435

CCc1ccc2[nH]c(Cc3ccccc3)nc2c1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.64
PKM P14618 3/20 0.55
TSHR P16473 1/20 0.55
GRIN1 Q05586 4/20 0.54
GRIN2B Q13224 4/20 0.54
MAPT P10636 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
KDM4E B2RXH2 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
LMNA P02545 1/20 0.54
EGFR P00533 1/20 0.52
ERBB2 P04626 1/20 0.52
DDAH1 O94760 1/20 0.50
POLB P06746 1/20 0.50
RIPK1 Q13546 1/20 0.49
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8974447 0.88 GAA (0.67) GAAPKMTSHRGRIN1GRIN2B
SCHEMBL8973973 0.87 RAB9A (0.65) GAAMAPTSMN1; SMN2NPC1RAB9A
SCHEMBL13991771 0.85 GAA (0.64) GAAPKMTSHRGRIN1GRIN2B
SCHEMBL5795499 0.85 GAA (0.64) GAAPKMTSHRGRIN1GRIN2B
SCHEMBL8973995 0.84 GAA (0.68) GAAPKMTSHRGRIN1GRIN2B
SCHEMBL3266627 0.84 DDAH1 (0.59) GAAMAPTSMN1; SMN2NPC1RAB9A
SCHEMBL8620324 0.84 GAA (0.55) GAAPKMTSHRGRIN1GRIN2B
SCHEMBL5081088 0.80 GAA (0.66) GAAPKMTSHRGRIN1GRIN2B
SCHEMBL4164834 0.80 GAA (0.66) GAAPKMTSHRGRIN1GRIN2B
SCHEMBL19884911 0.80 GAA (0.66) GAAPKMTSHRGRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0551112-B1 Benzimidazole derivative and composition for treating copper and copper alloy surfaces comprising the same MEC CO LTD (JP) 1996-04-03 EP disclosed
US-5476947-A Excellent rust preventing effect, useful as corrosion resistance protective coating in printed wiring boards MEC CO., LTD. (JP) 1995-12-19 US disclosed
US-5435860-A Corrosion resistance for printed circuits MEC CO., LTD. (JP) 1995-07-25 US disclosed
EP-0551112-A1 Benzimidazole derivative and composition for treating copper and copper alloy surfaces comprising the same MEC CO., Ltd. (JP) 1993-07-14 EP disclosed