Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.72 |
| ▸ | CA9 | Q16790 | 14/20 | 0.72 |
| ▸ | CA12 | O43570 | 12/20 | 0.72 |
| ▸ | CA1 | P00915 | 12/20 | 0.72 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8974082 | 0.85 | CA2 (0.52) | CA2CA9CA12CA1MAOA | |
| SCHEMBL8974324 | 0.85 | CA2 (0.52) | CA2CA9CA12CA1MAOA | |
| SCHEMBL8974143 | 0.84 | PTGS2 (0.63) | CA2CA9CA12CA1MAOA | |
| SCHEMBL329973 | 0.82 | CA2 (0.88) | CA2CA9CA12CA1MAOA | |
| Ammonia Solution, Strong SCHEMBL27578396 | 0.80 | CA2 (0.84) | CA2CA9CA12CA1MAOA | |
| SCHEMBL8974661 | 0.80 | CA1 (0.45) | CA2CA9CA12CA1MAOA | |
| SCHEMBL8974782 | 0.80 | CA2 (0.68) | CA2CA9CA12CA1MAOA | |
| SCHEMBL8974243 | 0.80 | CA2 (0.71) | CA2CA9CA12CA1CA4 | |
| SCHEMBL8974406 | 0.78 | PTGS2 (0.60) | CA2CA9CA12CA1MAOA | |
| SCHEMBL8974750 | 0.78 | CA2 (0.64) | CA2CA9CA12CA1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576339-A | Pyridyl substituted cyclopentadienes for the treatment of inflamation | HUANG HORNG-CHIH (US) | 1996-11-19 | — | — | US | disclosed |
| WO-1995030656-A1 | SUBSTITUTED CYCLOPENTADIENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-11-16 | — | — | WO | disclosed |