Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383981 | 0.85 | — | — | |
| SCHEMBL9331783 | 0.79 | RAB9A (0.34) | CYP2C9MAPTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL7076631 | 0.76 | OPRM1 (0.44) | CYP1A2DRD2OPRM1DRD3MAPT | |
| SCHEMBL1954071 | 0.76 | CYP2C9 (0.41) | CYP2C9CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL25005769 | 0.70 | MEN1 (0.32) | CYP1A2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4192907 | 0.68 | ESR1 (0.54) | CYP1A2MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL10471663 | 0.67 | SLC2A1 (0.48) | MEN1KMT2ADRD2OPRM1DRD3 | |
| SCHEMBL396913 | 0.67 | CHRM2 (0.51) | CYP2C9CYP1A2KMT2ADRD2OPRM1 | |
| SCHEMBL31607611 | 0.67 | HSP90AA1 (0.39) | CYP2C9CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL28812645 | 0.67 | OPRM1 (0.41) | CYP2C9CYP1A2DRD2OPRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618899-B1 | AROMATIC ESTERS OF PHENYLENEDIALKANOATES AS INHIBITORS OF HUMAN NEUTROPHIL ELASTASE | CORTECH INC (US) | 1996-03-13 | — | — | EP | disclosed |