Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21583436 | 0.80 | ACMSD (0.42) | DHODHHSD11B1GABRPGABRDGABRA1 | |
| SCHEMBL20898069 | 0.79 | HSD11B1 (0.51) | GRM2HSD11B1GABRPGABRDGABRA1 | |
| SCHEMBL31067088 | 0.79 | HSD11B1 (0.51) | GRM2HSD11B1GABRPGABRDGABRA1 | |
| SCHEMBL8974517 | 0.78 | KMO (0.42) | GRM2HSD11B1 | |
| SCHEMBL31067119 | 0.76 | HSD11B1 (0.49) | HSD11B1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL20898552 | 0.76 | HSD11B1 (0.49) | HSD11B1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31067193 | 0.74 | PBRM1 (0.44) | CYP1A2CYP2C9CYP2C19LMNASMN1; SMN2 | |
| SCHEMBL16013714 | 0.74 | CYP3A4 (0.39) | HSD11B1ALDH1A1CYP1A2 | |
| SCHEMBL17407435 | 0.74 | PDK2 (0.47) | DHODHHSD11B1CYP1A2L3MBTL1MBNL1 | |
| SCHEMBL31067126 | 0.74 | PTPRC (0.42) | DHODHHSD11B1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5540838-A | Stimulation of microbial para-dechlorination of polychlorinated biphenyls | GENERAL ELECTRIC COMPANY (US) | 1996-07-30 | — | — | US | disclosed |