Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 2/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | ADCYAP1R1 | P41586 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4077149 | 0.78 | SLC5A2 (0.46) | CETP | |
| SCHEMBL8768492 | 0.76 | TSHR (0.44) | KIF11NOTUMDRD4CETPABCC9 | |
| SCHEMBL3147185 | 0.74 | GPR3 (0.50) | KIF11SLC22A12EPHX2GPR3CETP | |
| Ethyne SCHEMBL28472442 | 0.72 | KIF11 (0.44) | KIF11EPHX2GPR3KDM1A | |
| SCHEMBL25046792 | 0.72 | HTR2C (0.45) | NOTUMDRD4 | |
| SCHEMBL13092310 | 0.72 | TACR1 (0.39) | KIF11EPHX2NOTUMDRD4CETP | |
| SCHEMBL20282990 | 0.72 | KCNH2 (0.48) | NOTUMDRD4KDM1A | |
| SCHEMBL27862141 | 0.72 | KIF11 (0.47) | KIF11EPHX2GPR3KDM1A | |
| SCHEMBL168125 | 0.72 | KIF11 (0.47) | KIF11EPHX2GPR3KDM1A | |
| SCHEMBL5670014 | 0.72 | CETP (0.54) | KIF11CETPMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482971-A | Beta3 -adrenergic agents and their use in pharmaceutical compositions | AMERICAN CYANAMID COMPANY (US) | 1996-01-09 | — | — | US | disclosed |