Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.37 |
| ▸ | MEN1 | O00255 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | POLB | P06746 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377354 | 0.79 | MAPT (0.46) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29456982 | 0.79 | MAPT (0.46) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9246536 | 0.79 | MAPT (0.46) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8830256 | 0.76 | TSHR (0.43) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8830303 | 0.74 | MAPT (0.42) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14440013 | 0.71 | CXCL8 (0.43) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL8916681 | 0.70 | ITGB1 (0.44) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11481793 | 0.69 | KDM4E (0.51) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL8830164 | 0.68 | KDM4E (0.43) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11210924 | 0.67 | NPC1 (0.44) | KMT2AMEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552430-A | ANTIRETROVIRAL COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-09-03 | — | — | US | claimed |