SCHEMBL377354

SCHEMBL377354

NC(=O)C(Nc1ccccc1[N+](=O)[O-])c1c(Cl)cccc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
MAPK1 P28482 1/20 0.46
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
LMNA P02545 2/20 0.45
PHGDH O43175 1/20 0.45
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
ALDH1A1 P00352 2/20 0.43
XBP1 P17861 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
KCNMA1 Q12791 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29456982 1.00 MAPT (0.46) MAPTL3MBTL1MAPK1NPC1RAB9A
SCHEMBL9246536 1.00 MAPT (0.46) MAPTL3MBTL1MAPK1NPC1RAB9A
SCHEMBL9030000 0.88 MAPT (0.47) MAPTL3MBTL1MAPK1NPC1RAB9A
SCHEMBL8830256 0.86 TSHR (0.43) MAPTL3MBTL1MAPK1LMNAPHGDH
SCHEMBL8830303 0.84 MAPT (0.42) MAPTNPC1RAB9ALMNAMEN1
SCHEMBL9068299 0.83 MAPT (0.45) MAPTL3MBTL1MAPK1NPC1RAB9A
SCHEMBL8916681 0.80 ITGB1 (0.44) MAPTMAPK1NPC1RAB9ALMNA
SCHEMBL14440013 0.79 CXCL8 (0.43) MAPTMAPK1LMNAALDH1A1HTT
SCHEMBL9032150 0.79 LMNA (0.49) MAPTL3MBTL1MAPK1NPC1RAB9A
SCHEMBL8974822 0.79 KMT2A (0.37) MAPTL3MBTL1MAPK1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 297 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3808743-A1 HIV REPLICATION INHIBITING PYRIMIDINES Janssen Pharmaceutica NV (BE) 2021-04-21 EP claimed
US-9938528-B2 Methods and pharmaceutical compositions for treating human immunodeficiency virus type 1 (HIV-1) infections INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2018-04-10 US claimed
US-20170342411-A1 Methods and Pharmaceutical Compositions for Treating Human Immunodeficiency Virus Type 1 (HIV-1) Infections ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP) (FR) 2017-11-30 US claimed
EP-3230455-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) INFECTIONS Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2017-10-18 EP claimed
WO-2016092041-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) INFECTIONS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2016-06-16 WO claimed
US-7037917-B2 HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICA, N.V. (BE) 2006-05-02 US claimed
US-6962916-B2 Substituted diamino-1,3,5-triazine derivatives JANSSEN PHARMACEUTICA N.V. (BE) 2005-11-08 US claimed
US-20040039005-A1 Nitrogen compounds such as 4-((4-amino-5-bromo-6-(4-cyano-2,6-dimethylphenyloxy)-2 -pyrimidinyl)amino)benzonitrile, used as protease inhibitors for prophylaxis of viral diseases JANSSEN PHARMACEUTICA N.V. (BE) 2004-02-26 US claimed
US-20030199473-A1 Substituted diamino-1,3,5-triazine derivatives JANSSEN PHARMACEUTICA N.V. 2003-10-23 US claimed
EP-0684818-B1 METHOD OF REVERSING RESISTANCE OF HIV-1 STRAINS TO ZIDOVUDINE JANSSEN PHARMACEUTICA NV (BE) 1999-05-06 EP claimed
US-5684049-A HIV-inhibiting benzeneacetamide derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1997-11-04 US claimed
EP-0538301-B1 HIV-INHIBITING BENZENEACETAMIDE DERIVATIVES JANSSEN PHARMACEUTICA NV (BE) 1996-10-30 EP claimed
US-5556886-A VIRICIDES JANSSEN PHARMACEUTICA N.V. (BE) 1996-09-17 US claimed
EP-0684818-A1 METHOD OF REVERSING RESISTANCE OF HIV-1 STRAINS TO ZIDOVUDINE JANSSEN PHARMACEUTICA N.V. (BE) 1995-12-06 EP claimed
CN-1107835-A A process for preparing pharmaceutical composition showing properties in against human immunodeficiency virus JANSSEN PHARMACEUTICA NV (BE) 1995-09-06 CN claimed
EP-0666744-A1 USE OF BHAP COMPOUNDS IN COMBINATION WITH OTHER NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS FOR THE TREATMENT OF HIV INFECTION THE UPJOHN COMPANY (US) 1995-08-16 EP claimed
CN-1028990-C Process for preparing phenylacetamide derivatives for inhibiting human immunodeficiency virus JANSSEN PHARMACEUTICA NV (BE) 1995-06-21 CN claimed
WO-1994018963-A1 METHOD OF REVERSING RESISTANCE OF HIV-1 STRAINS TO ZIDOVUDINE JANSSEN PHARMACEUTICA N.V. (BE) 1994-09-01 WO claimed
WO-1994009781-A1 USE OF BHAP COMPOUNDS IN COMBINATION WITH OTHER NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS FOR THE TREATMENT OF HIV INFECTION THE UPJOHN COMPANY (US) 1994-05-11 WO claimed
EP-3528791-B1 DISPERSIBLE COMPOSITIONS JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) 2023-12-06 EP disclosed
EP-4248947-A2 DISPERSIBLE COMPOSITIONS Janssen Sciences Ireland Unlimited Company (IE) 2023-09-27 EP disclosed
CN-111565716-B Method of using dipivefrin 因斯格尼斯疗法有限公司 2023-06-09 CN disclosed
EP-1663240-B2 COMBINATIONS OF A PYRIMIDINE CONTAINING NNRTI WITH RT INHIBITORS JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) 2023-03-01 EP disclosed
EP-3808743-B1 HIV REPLICATION INHIBITING PYRIMIDINES JANSSEN PHARMACEUTICA NV (BE) 2022-07-20 EP disclosed
EP-1632232-B3 Salt of 4[[4-[[4-(2-Cyanoethenyl)-2,6-dimethylphenyl]amino]-2-Pyrimidinyl]amino]benzonitrile JANSSEN PHARMACEUTICA NV (BE) 2022-03-30 EP disclosed
US-20220008333-A1 DISPERSIBLE COMPOSITIONS JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) 2022-01-13 US disclosed
US-20220008417-A1 COMBINATIONS OF A PYRIMIDINE CONTAINING NNRTI WITH RT INHIBITORS Janssen Sciences Ireland Unlimited Company (IE) 2022-01-13 US disclosed
US-11065198-B2 Dispersible compositions Janssen Sciences Ireland Unlimited Company (IE) 2021-07-20 US disclosed
EP-3808743-A1 HIV REPLICATION INHIBITING PYRIMIDINES Janssen Pharmaceutica NV (BE) 2021-04-21 EP disclosed
US-20200345733-A1 Microbicidal Pyrimidine or Triazine Containing Compounds Janssen Sciences Ireland Unlimited Company (IE) 2020-11-05 US disclosed
US-20200171027-A1 COMBINATIONS OF A PYRIMIDINE CONTAINING NNRTI WITH RT INHIBITORS Janssen Sciences Ireland Unlimited Company (IE) 2020-06-04 US disclosed
US-10611732-B2 HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICA NV (BE) 2020-04-07 US disclosed
EP-2298761-B1 HIV INHIBITING PYRIMIDINES DERIVATIVES JANSSEN PHARMACEUTICA NV (BE) 2020-03-25 EP disclosed
US-20200069579-A1 DISPERSIBLE COMPOSITIONS JANSSEN PHARMACEUTICA NV (BE) 2020-03-05 US disclosed
US-20190322628-A1 HIV REPLICATION INHIBITING PYRIMIDINES JANSSEN PHARMACEUTICA NV (BE) 2019-10-24 US disclosed
EP-3528791-A1 DISPERSIBLE COMPOSITIONS Janssen Sciences Ireland Unlimited Company (IE) 2019-08-28 EP disclosed
US-10370340-B2 HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICA NV (BE) 2019-08-06 US disclosed
US-20190216807-A1 COMBINATIONS OF A PYRIMIDINE CONTAINING NNRTI WITH RT INHIBITORS JANSSEN SCIENCES IRELAND UC (IE) 2019-07-18 US disclosed
US-10077270-B2 HIV inhibiting bicyclic pyrimidine derivatives JANSSEN SCIENCES IRELAND UC (IE) 2018-09-18 US disclosed
US-10072015-B2 HIV inhibiting bicyclic pyrimidine derivatives JANSSEN SCIENCES IRELAND UC (IE) 2018-09-11 US disclosed
US-20180244632-A1 HIV REPLICATION INHIBITING PYRIMIDINES JANSSEN PHARMACEUTICA NV (BE) 2018-08-30 US disclosed
US-9981919-B2 HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICAL N.V. (BE) 2018-05-29 US disclosed
WO-2018077815-A1 DISPERSIBLE COMPOSITIONS JANSSEN SCIENCES IRELAND UC (IE) 2018-05-03 WO disclosed
US-20180116964-A1 SALT OF 4-[[4-[[4-(2-CYANOETHENYL)-2,6-DIMETHYLPHENYL]AMINO]-2-PYRIMIDINYL]AMINO]BENZONITRILE JANSSEN PHARMACEUTICA NV (BE) 2018-05-03 US disclosed
US-9938528-B2 Methods and pharmaceutical compositions for treating human immunodeficiency virus type 1 (HIV-1) infections INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2018-04-10 US disclosed
US-20180036427-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF HIV INFECTION UNIVERSITÉ DE BORDEAUX (FR) 2018-02-08 US disclosed
US-20180016281-A1 HIV INHIBITING BICYCLIC PYRIMIDINE DERIVATIVES JANSSEN SCIENCES IRELAND UC (IE) 2018-01-18 US disclosed
US-20180009819-A1 HIV INHIBITING BICYCLIC PYRIMIDINE DERIVATIVES JANSSEN SCIENCES IRELAND UC (IE) 2018-01-11 US disclosed
EP-3265566-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF HIV INFECTION INSERM - Institut National de la Santé et de la Recherche Médicale (FR) 2018-01-10 EP disclosed
US-20170342411-A1 Methods and Pharmaceutical Compositions for Treating Human Immunodeficiency Virus Type 1 (HIV-1) Infections ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP) (FR) 2017-11-30 US disclosed
US-20170320835-A1 HIV REPLICATION INHIBITING PYRIMIDINES JANSSEN PHARMACEUTICA NV (BE) 2017-11-09 US disclosed
US-9802943-B2 HIV inhibiting bicyclic pyrimidine derivatives JANSSEN SCIENCES IRELAND UC (IE) 2017-10-31 US disclosed
EP-3230455-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) INFECTIONS Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2017-10-18 EP disclosed
US-20170191059-A1 NUCLEIC ACIDS ACTING AS DECOYS FOR THE TREATMENT OF LENTIVIRUS INFECTION Universite de Bordeaux (FR) 2017-07-06 US disclosed
US-20170121292-A1 HIV REPLICATION INHIBITING PYRIMIDINES JANSSEN PHARMACEUTICA NV (BE) 2017-05-04 US disclosed
US-20170100398-A1 COMBINATIONS OF A PYRIMIDINE CONTAINING NNRTI WITH RT INHIBITORS JANSSEN SCIENCES IRELAND UC (IE) 2017-04-13 US disclosed
US-20170100399-A1 Microbicidal Pyrimidine Or Triazine Containing Compounds Janssen Sciences Ireland Unlimited Company (IE) 2017-04-13 US disclosed
EP-3146048-A2 NUCLEIC ACIDS ACTING AS DECOYS FOR THE TREATMENT OF LENTIVIRUS INFECTION INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2017-03-29 EP disclosed
US-9580392-B2 HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICA NV (BE) 2017-02-28 US disclosed
US-20160355519-A1 HIV INHIBITING BICYCLIC PYRIMIDINE DERIVATIVES JANSSEN SCIENCES IRELAND UC (IE) 2016-12-08 US disclosed
US-9487518-B2 HIV inhibiting bicyclic pyrimidine derivatives JANSSEN SCIENCES IRELAND UC (IE) 2016-11-08 US disclosed
EP-1597237-B1 Pyrimidine derivatives for the prevention of HIV infection JANSSEN PHARMACEUTICA NV (BE) 2016-07-27 EP disclosed
WO-2016092041-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) INFECTIONS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2016-06-16 WO disclosed
WO-2015177331-A2 NUCLEIC ACIDS ACTING AS DECOYS FOR THE TREATMENT OF LENTIVIRUS INFECTION INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2015-11-26 WO disclosed
EP-1282607-B1 PRODRUGS OF HIV REPLICATION INHIBITING PYRIMIDINES JANSSEN PHARMACEUTICA NV (BE) 2015-11-11 EP disclosed
US-20150283135-A1 Combinations Of A Pyrimidine Containing NNRTI With RT Inhibitors JANSEN SCIENCES IRELAND UC (IE) 2015-10-08 US disclosed
EP-2603587-B1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF HIV-1 INFECTIONS INSERM INST NAT DE LA SANTÉ ET DE LA RECH MÉDICALE (FR) 2015-10-07 EP disclosed
EP-1282606-B1 HIV REPLICATION INHIBITING PYRIMIDINES AND TRIAZINES JANSSEN PHARMACEUTICA NV (BE) 2015-04-22 EP disclosed
EP-1663240-B1 COMBINATIONS OF A PYRIMIDINE CONTAINING NNRTI WITH RT INHIBITORS JANSSEN SCIENCES IRELAND UC (IE) 2015-04-22 EP disclosed
US-8946248-B2 HIV inhibiting 5-substituted pyrimidines JANSSEN R&D IRELAND (IR) 2015-02-03 US disclosed
EP-1853567-B1 HIV INHIBITING 2-(4-CYANOPHENYLAMINO) PYRIMIDINE OXIDE DERIVATIVES JANSSEN R & D IRELAND (IE) 2014-12-31 EP disclosed
US-20140349971-A1 Combinations of A Pyrimidine Containing NNRTI with RT Inhibitors JANSSEN SCIENCES IRELAND UC (IE) 2014-11-27 US disclosed
US-20140343006-A1 HIV Replication Inhibiting Pyrimidines JANSSEN PHARMACEUTICA NV (NL) 2014-11-20 US disclosed
US-8841310-B2 Combinations of a pyrimidine containing NNRTI with RT inhibitors JANSSEN R & D IRELAND (IE) 2014-09-23 US disclosed
US-8828982-B2 Pyrimidine derivatives for the prevention of HIV infection JANSSEN PHARMACEUTICA N.V. (BE) 2014-09-09 US disclosed
EP-1807430-B1 HIV INHIBITING BICYCLIC PYRIMIDINE DERIVATIVES JANSSEN R & D IRELAND (IE) 2014-07-23 EP disclosed
US-8575342-B2 HIV inhibiting 5-heterocyclyl pyrimidines TIBOTECH PHARMACEUTICALS LTD. (IE) 2013-11-05 US disclosed
EP-1797050-B1 HIV INHIBITING 1.2.4-TRIAZIN-6-ONE DERIVATES JANSSEN PHARMACEUTICA NV (BE) 2013-10-23 EP disclosed
US-8530655-B2 HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICA NV (BE) 2013-09-10 US disclosed
US-20130156791-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF HIV-1 INFECTIONS INSTITUT PASTEUR (FR) 2013-06-20 US disclosed
EP-2603587-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF HIV-1 INFECTIONS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2013-06-19 EP disclosed
CN-101027288-B HIV inhibiting 5-substituted pyrimidines TIBOTEC PHARM LTD 2013-04-17 CN disclosed
US-20120190697-A1 HIV INHIBITING BICYCLIC PYRIMIDINE DERIVATIVES JANSSEN SCIENCES IRELAND UC (IE) 2012-07-26 US disclosed
CN-102558070-A Microbicidal pyrimidine or triazine for preventing sexual HIV transmission TIBOTEC PHARM LTD 2012-07-11 CN disclosed
CN-101133038-B HIV inhibiting 2-(4-cyanophenyl)-6-hydroxylaminopyrimidines TIBOTEC PHARM LTD 2012-06-27 CN disclosed
US-8153640-B2 Reverse transcriptase inhibitors; use against HIV with drug resistance to NNRTI's (Non Nucleoside Reverse Transcriptase Inhibitor drugs); Diaryl Pyrrolo(2,3-d)pyrimidines, diaryl purines, diaryl v-triazolo(4,5-d)pyrimidines TIBOTEC PHARMACEUTICALS LTD. (IE) 2012-04-10 US disclosed
US-20120076835-A1 HIV INHIBITING PYRIMIDINES DERIVATIVES GUILLEMONT JEROME EMILE GEORGES (FR) 2012-03-29 US disclosed
EP-1789139-B1 FUMARATE OF 4-((4-((4-(2-CYANOETHENYL)-2,6-DIMETHYLPHENYL AMINO -2-PYRIMIDINYL AMINO BENZONITRILE JANSSEN PHARMACEUTICA NV (BE) 2012-03-21 EP disclosed
US-8119801-B2 HIV inhibiting 2-(4-cyanophenyl)-6-hydroxylaminopyrimidines TIBOTEC PHARMACEUTICALS LTD. (IE) 2012-02-21 US disclosed
WO-2012019991-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF HIV-1 INFECTIONS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2012-02-16 WO disclosed
EP-1797047-B1 HIV INHIBITING 5-SUBSTITUTED PYRIMIDINES TIBOTEC PHARM LTD (IE) 2012-01-25 EP disclosed
US-8101629-B2 Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile JANSSEN PHARMACEUTICA N.V. (BE) 2012-01-24 US disclosed
EP-1838709-B1 1,5,6-SUBSTITUTED-2-OXO-3-CYANO-1,6A-DIAZA-TETRAHYDRO-FLUORANTHENES AS ANTI-INFECTIVE AGENTS TIBOTEC PHARM LTD (IE) 2011-12-21 EP disclosed
US-8080551-B2 HIV inhibiting pyrimidines derivatives JANSSEN PHARMACEUTICA N.V. (BE) 2011-12-20 US disclosed
EP-2388249-A1 HIV inhibiting 2-(4-cyanophenylamino) pyrimidine derivatives Tibotec Pharmaceuticals (IE) 2011-11-23 EP disclosed
US-20110263625-A1 HIV REPLICATION INHIBITING PYRIMIDINES CORTE BART DE 2011-10-27 US disclosed
US-20110255174-A1 Display Device with an Optical Combiner Corrected for Chromatic Aberrations THALES (FR) 2011-10-20 US disclosed
US-8036861-B2 Using phenotypic marker concentration as evaluative tool in measuring propagation progression of viral nucleotide sequences; diagnosing microorganismal infection TIBOTEC PHARMACEUTICALS (IE) 2011-10-11 US disclosed
US-8026248-B2 4-[[4-[(2,6-dichloro-phenyl)methyl]-6-[[2-(1-pyrrolidinyl)ethyl]amino]-2-pyrimidinyl]amino]benzonitrile; 4-[[4-[(2,4,6-trimethylphenyl)amino]-2-pyrimidinyl]amino]benzamide, N1-oxide combined with another retrovirus inhibitor; viricides; treatment of AIDS JANSSEN PHARMACEUTICA N.V. (BE) 2011-09-27 US disclosed
US-8026245-B2 HIV replication inhibiting purine derivatives JANSSEN PHARMACEUTICA N.V. (BE) 2011-09-27 US disclosed
EP-1853568-B1 HIV INHIBITING 2-(4-CYANOPHENYLAMINO)PYRIMIDINE DERIVATIVES TIBOTEC PHARM LTD (IE) 2011-09-07 EP disclosed
US-8003789-B2 HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICA, N.V. (BE) 2011-08-23 US disclosed
EP-1797069-B1 HIV INHIBITING 5-HETEROCYCLYL PYRIMIDINES TIBOTEC PHARM LTD (IE) 2011-08-17 EP disclosed
EP-1797048-B1 HIV INHIBITING 5-CARBO- OR HETEROCYCLIC SUBSTITUTED PYRIMIDINES TIBOTEC PHARM LTD (IE) 2011-08-17 EP disclosed
EP-1419152-B1 HIV INHIBITING PYRIMIDINES DERIVATIVES JANSSEN PHARMACEUTICA NV (BE) 2011-07-27 EP disclosed
US-20110165093-A1 MICROBICIDAL PYRIMIDINE OR TRIAZINE FOR PREVENTING SEXUAL HIV TRANSMISSION TIBOTEC PHARMACEUTICALS LTD. (IE) 2011-07-07 US disclosed
US-20110150996-A1 SALT OF 4-[[4-[[4-(2-CYANOETHENYL)-2,6-DIMETHYLPHENYL]AMINO] -2-PYRIMIDINYL]AMINO]BENZONITRILE STEVENS PAUL THEODOOR AGNES 2011-06-23 US disclosed
US-7956063-B2 Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile JANSSEN PHARMACEUTICA NV (BE) 2011-06-07 US disclosed
EP-1632232-B1 Salt of 4[[4-[[4-(2-Cyanoethenyl)-2,6-dimethylphenyl]amino]-2-Pyrimidinyl]amino]benzonitrile JANSSEN PHARMACEUTICA NV (BE) 2011-05-11 EP disclosed
US-7935710-B2 Microbicidal pyrimidine or triazine for preventing sexual HIV transmission TIBOTEC PHARMACEUTICALS LTD. (IE) 2011-05-03 US disclosed
US-7935711-B2 HIV inhibiting 2-(4-cyanophenylamino) pyrimidine oxide derivatives TIBOTEC PHARMACEUTICALS LTD. (IE) 2011-05-03 US disclosed
US-7923554-B2 HIV inhibiting 1,2,4-triazin-6-one derivatives JANSSEN PHARMACEUTICA N.V. (BE) 2011-04-12 US disclosed
EP-2298761-A1 HIV inhibiting pyrimidines derivatives Janssen Pharmaceutica NV (BE) 2011-03-23 EP disclosed
EP-1245567-B1 HIV inhibiting pyrimidine derivatives JANSSEN PHARMACEUTICA NV (BE) 2011-03-02 EP disclosed
EP-1668011-B1 HIV REPLICATION INHIBITING PURINE DERIVATIVES JANSSEN PHARMACEUTICA NV (BE) 2011-03-02 EP disclosed
US-7887845-B2 Particle of a solid dispersion composed of a water soluble polymer and etravirine or salt thereof; etravirine FDA Orange book listed patent JANSSEN PHARMACEUTICA NV (BE) 2011-02-15 US disclosed
US-20110008434-A1 SALT OF 4-[[4-[[4-(2-CYANOETHENYL)-2,6-DIMETHYLPHENYL]AMINO]-2-PYRIMIDINYL]AMINO]BENZONITRILE GUILLEMONT JEROME EMILE GEORGES 2011-01-13 US disclosed
US-7763631-B2 Prodrugs of HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICA NV (BE) 2010-07-27 US disclosed
US-20100172970-A1 ANTIVIRAL COMPOSITIONS VERRECK GEERT 2010-07-08 US disclosed
EP-1858861-B1 HIV INHIBITING 2-(4-CYANOPHENYL)-6-HYDROXYLAMINOPYRIMIDINES TIBOTEC PHARM LTD (IE) 2010-07-07 EP disclosed
US-20100121060-A1 HIV INHIBITING 2-(4-CYANOPHENYL)-6-HYDROXYLAMINOPYRIMIDINES JANSSEN SCIENCES IRELAND UC (IE) 2010-05-13 US disclosed
US-20100034810-A1 PYRIMIDINE DERIVATIVES FOR THE PREVENTION OF HIV INFECTION JANSSEN-CILAG (FR) 2010-02-11 US disclosed
US-20100029591-A1 COMBINATIONS OF A PYRIMIDINE CONTAINING NNRTI WITH RT INHIBITORS JANSSEN SCIENCES IRELAND UC (IE) 2010-02-04 US disclosed
US-20100009341-A1 METHODS AND MEANS FOR ASSESSING HIV GAG/PROTEASE INHIBITOR THERAPY TIBOTEC BVBA (BE) 2010-01-14 US disclosed
EP-1270560-B1 Hiv replication inhibiting pyrimidines JANSSEN PHARMACEUTICA NV (BE) 2010-01-13 EP disclosed
US-7638522-B2 Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino] benzonitrile JANSSEN PHARMACEUTICA N.V. (BE) 2009-12-29 US disclosed
US-7585861-B2 HIV replication inhibitors; for (multi)drug resistant HIV infection JANSSEN PHARMACEUTICA, N.V. (BE) 2009-09-08 US disclosed
US-20090215804-A1 FUMARATE OF 4- [[4- [[4- (2-CYANOETHENYL) -2,6-DIMETHYLPHENYL)AMINO] -2-PYRIMIDINYL]AMINO]BENZONITRILE JANSSEN PHARMACEUTICA N.V. (BE) 2009-08-27 US disclosed
US-20090181993-A1 HIV INHIBITING 5-HETEROCYCLYL PYRIMIDINES JANSSEN SCIENCES IRELAND UC (IE) 2009-07-16 US disclosed
US-20090124644-A1 HIV INHIBITING 2-(4-CYANOPHENYLAMINO) PYRIMIDINE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2009-05-14 US disclosed
EP-1946111-B1 METHOD AND MEANS FOR DETERMINING THE REPLICATION RATE OF A VIRAL POPULATION TIBOTEC PHARM LTD (IE) 2009-05-13 EP disclosed
US-7531548-B2 HIV inhibiting 5-carbo- or heterocyclic substituted pyrimidines TIBOTEC PHARMACEUTICALS LTD (IE) 2009-05-12 US disclosed
US-7514427-B2 1,5,6,-substituted-2-oxo-3-cyano-1,6a-diaza-tetrahydro-fluoranthenes as anti-inflective agents TIBOTEC PHARMACEUTICALS, LTD. (IE) 2009-04-07 US disclosed
US-20090012092-A1 Hiv Inhibiting 1,2,4-Triazin-6-One Derivatives JANSSEN PHARMACEUTICA N.V. (BE) 2009-01-08 US disclosed
US-20090012108-A1 SALT OF 4-[[4-[[4-(2-CYANOETHENYL)-2,6-DIMETHYLPHENYL]AMINO]-2-PYRIMIDINYL]AMINO]BENZONITRILE GUILLEMONT JEROME EMILE 2009-01-08 US disclosed
EP-2010680-A2 METHODS AND MEANS FOR ASSESSING HIV GAG/PROTEASE INHIBITOR THERAPY Tibotec Pharmaceuticals Ltd. (IE) 2009-01-07 EP disclosed
US-7449575-B2 Substituted diamino-1,3,5-triazine derivatives JANSSEN PHARMACEUTICA, INC. (BE) 2008-11-11 US disclosed
US-20080262007-A1 Hiv Inhibiting 5-Substituted Pyrimidines JANSSEN SCIENCES IRELAND UC (IE) 2008-10-23 US disclosed
US-20080220412-A1 Method and Means for Determining the Replication Rate of a Viral Population JANSSEN SCIENCES IRELAND UC (IE) 2008-09-11 US disclosed
US-20080214588-A1 Hiv Inhibiting 2-(4-Cyanophenyl)-6-Hydroxylaminopyrimidines TIBOTEC BVBA (BE) 2008-09-04 US disclosed
US-20080200435-A1 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]-amino]-2-pyrimidinyl]-amino]-benzonitrile with nucleoside and/or nucleotide reverse transcriptase inhibitors; prevention of HIV transmission; pharmacokinetic profile allowing once daily dosing TIBOTEC PHARMACEUTICALS LTD., A CORPORATION 2008-08-21 US disclosed
US-20080194602-A1 Hiv Inhibiting 2-(4-Cyanophenylamino) Pyrimidine Oxide Derivatives SONY CORPORATION (JP) 2008-08-14 US disclosed
US-20080176880-A1 Activity against strains having acquired resistance nonnucleoside reverse transcriptase inhibitors; human alpha1 acid glycoprotein nonbinding; such as 4-[[(5-bromo-4,6-dichloro)-2-pyrimidinyl]amino]-benzonitrile JANSSEN PHARMACEUTICA, N.V. (BE) 2008-07-24 US disclosed
EP-1597242-B1 HIV INHIBITING 1,2,4-TRIAZINES JANSSEN PHARMACEUTICA NV (BE) 2008-07-23 EP disclosed
EP-1946111-A1 METHOD AND MEANS FOR DETERMINING THE REPLICATION RATE OF A VIRAL POPULATION Tibotec Pharmaceuticals Ltd. (IE) 2008-07-23 EP disclosed
US-20080167296-A1 1,5,6,-Substituted-2-Oxo-3-Cyano-1,6a-Diaza-Tetrahydro-Fluoranthenes as Anti-Infective Agents TIBOTEC PHARMACEUTICALS LTD. (IE) 2008-07-10 US disclosed
US-20080085907-A1 Hiv Inhibiting Bicyclic Pyrimdine Derivatives JANSSEN-CILAG (FR) 2008-04-10 US disclosed
CN-101133038-A HIV inhibiting 2-(4-cyanophenyl)-6-hydroxylaminopyrimidines TIBOTEC PHARM LTD (IE) 2008-02-27 CN disclosed
EP-1858861-A1 HIV INHIBITING 2-(4-CYANOPHENYL)-6-HYDROXYLAMINOPYRIMIDINES Tibotec Pharmaceuticals Ltd. (IE) 2007-11-28 EP disclosed
EP-1853568-A1 HIV INHIBITING 2-(4-CYANOPHENYLAMINO) PYRIMIDINE DERIVATIVES Tibotec Pharmaceuticals Ltd. (IE) 2007-11-14 EP disclosed
EP-1853567-A1 HIV INHIBITING 2-(4-CYANOPHENYLAMINO) PYRIMIDINE OXIDE DERIVATIVES Tibotec Pharmaceuticals Ltd. (IE) 2007-11-14 EP disclosed
WO-2007118849-A2 METHODS AND MEANS FOR ASSESSING HIV GAG/PROTEASE INHIBITOR THERAPY TIBOTEC PHARMACEUTICALS LTD. (IE) 2007-10-25 WO disclosed
EP-1505980-B1 MICROBICIDAL PYRIMIDINE OR TRIAZINE FOR PREVENTING SEXUAL HIV TRANSMISSION TIBOTEC PHARM LTD (IE) 2007-10-24 EP disclosed
WO-2007114978-A2 METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND PA-457 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-10-11 WO disclosed
EP-1838709-A2 1,5,6-SUBSTITUTED-2-OXO-3-CYANO-1,6A-DIAZA-TETRAHYDRO-FLUORANTHENES AS ANTI-INFECTIVE AGENTS Tibotec Pharmaceuticals Ltd. (IE) 2007-10-03 EP disclosed
US-7276510-B2 HIV replication inhibitors JANSSEN PHARMACEUTICA, INC. (BE) 2007-10-02 US disclosed
US-20070208022-A1 HIV INHIBITING 5-CARBO- OR HETEROCYCLYL SUBSTITUTED PYRIMIDINES TIBOTEC PHARMACEUTICALS LTD. (IE) 2007-09-06 US disclosed
CN-101027288-A HIV inhibiting 5-substituted pyrimidines TIBOTEC PHARM LTD (IE) 2007-08-29 CN disclosed
US-20070196478-A1 ANTIVIRAL COMPOSITIONS VERRECK GEERT 2007-08-23 US disclosed
EP-1819348-A1 METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND GW695634 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-08-22 EP disclosed
EP-1819333-A1 METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND GW873140 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-08-22 EP disclosed
EP-1819335-A1 METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND SCH-417690 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-08-22 EP disclosed
US-20070190523-A1 Method and compositions for identifying anti-hiv therapeutic compounds GILEAD SCIENCES, INC. 2007-08-16 US disclosed
US-20070190523-A1 Method and compositions for identifying anti-hiv therapeutic compounds GILEAD SCIENCES, INC. 2007-08-16 US disclosed
EP-1814549-A2 METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND UK-427, 857 Boehringer Ingelheim International GmbH (DE) 2007-08-08 EP disclosed
EP-1814548-A1 METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND REVERSET BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-08-08 EP disclosed
EP-1814547-A1 METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND DARUNAVIR BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-08-08 EP disclosed
EP-1812069-A2 METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND ETRAVIRINE Boehringer Ingelheim International GmbH (DE) 2007-08-01 EP disclosed
EP-1370265-B1 HIV INHIBITING PYRAZINONE DERIVATIVES JANSSEN PHARMACEUTICA NV (BE) 2007-07-25 EP disclosed
EP-1807430-A1 HIV INHIBITING BICYCLIC PYRIMIDINE DERIVATIVES Tibotec Pharmaceuticals Ltd. (IE) 2007-07-18 EP disclosed
US-7241458-B1 Antiviral compositions JANSSEN PHARMACEUTICA N.V. (BE) 2007-07-10 US disclosed
EP-1797050-A1 HIV INHIBITING 1.2.4-TRIAZIN-6-ONE DERIVATES JANSSEN PHARMACEUTICA N.V. (BE) 2007-06-20 EP disclosed
EP-1797069-A2 HIV INHIBITING 5-HETEROCYCLYL PYRIMIDINES Tibotec Pharmaceuticals Ltd. (IE) 2007-06-20 EP disclosed
EP-1797048-A2 HIV INHIBITING 5-CARBO- OR HETEROCYCLIC SUBSTITUTED PYRIMIDINES Tibotec Pharmaceuticals Ltd. (IE) 2007-06-20 EP disclosed
EP-1797047-A1 HIV INHIBITING 5-SUBSTITUTED PYRIMIDINES Tibotec Pharmaceuticals Ltd. (IE) 2007-06-20 EP disclosed
EP-1789139-A1 FUMARATE OF 4-((4-((4-(2-CYANOETHENYL)-2,6-DIMETHYLPHENYL|AMINO|-2-PYRIMIDINYL|AMINO|BENZONITRILE JANSSEN PHARMACEUTICA N.V. (BE) 2007-05-30 EP disclosed
WO-2007042568-A1 METHOD AND MEANS FOR DETERMINING THE REPLICATION RATE OF A VIRAL POPULATION TIBOTEC PHARMACEUTICALS LTD. (IE) 2007-04-19 WO disclosed
US-20070037811-A1 HIV replication inhibitors; for (multi)drug resistant HIV infection BMO BANK N.A., AS ADMINISTRATIVE AGENT 2007-02-15 US disclosed
US-20070021449-A1 Pyrimidine derivatives for the prevention of hiv infection HEERES JAN 2007-01-25 US disclosed
US-20060293330-A1 Hiv replication inhibiting purine derivatives JANSSEN PHARMACEUTICA N.V. (BE) 2006-12-28 US disclosed
US-20060252764-A1 HIV inhibiting pyrimidines derivatives GUILLEMONT JEROME E G 2006-11-09 US disclosed
US-7125879-B2 HIV inhibiting pyrimidines derivatives JANSSEN PHARMACEUTICA N.V. (BE) 2006-10-24 US disclosed
US-7115608-B2 Pyridinone and pyridinethione derivatives having HIV inhibiting properties CENTRE NATIONAL DE LA RECHERCHE SCHENTIFIQUE (FR) 2006-10-03 US disclosed
WO-2006094930-A1 HIV INHIBITING 2-(4-CYANOPHENYL)-6-HYDROXYLAMINOPYRIMIDINES TIBOTEC PHARMACEUTICALS LTD. (IE) 2006-09-14 WO disclosed
US-7105522-B2 HIV inhibiting pyrazinone derivatives JANSSEN PHARMACEUTICA, N.V. (BE) 2006-09-12 US disclosed
US-20060189614-A1 Substituted diamino-1,3,5-triazine derivatives JANSSEN PAUL A 2006-08-24 US disclosed
WO-2006087387-A1 HIV INHIBITING 2-(4-CYANOPHENYLAMINO) PYRIMIDINE OXIDE DERIVATIVES TIBOTEC PHARMACEUTICALS LTD. (IE) 2006-08-24 WO disclosed
WO-2006079656-A1 HIV INHIBITING 2-( 4-CYANOPHENYLAMINO) PYRIMIDINE DERIVATIVES TIBOTEC PHARMACEUTICALS LTD. (IE) 2006-08-03 WO disclosed
US-20060166943-A1 Microbicidal pyrimidine or triazine for preventing sexual hiv transmission TIBOTEC PHARMACEUTICALS LTD. (IE) 2006-07-27 US disclosed
US-20060160859-A1 Method for treating HIV infection through co-administration of tipranavir and GW873140 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-07-20 US disclosed
WO-2006072636-A2 1, 5, 6-SUBSTITUTED-2-OXO-3-CYANO-1, 6A-DIAZA-TETRAHYDRO-FLUORANTHENES AS ANTI-INFECTIVE AGENTS TIBOTEC PHARMACEUTICALS LTD. (IE) 2006-07-13 WO disclosed
US-20060142344-A1 Method for treating HIV infection through co-administration of tipranavir and GW695634 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-06-29 US disclosed
US-20060135562-A1 Method for treating HIV infection through co-administration of tipranavir and darunavir BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-06-22 US disclosed
US-20060135563-A1 Method for treating HIV infection through co-administration of tipranavir and SCH-417690 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-06-22 US disclosed
US-20060127487-A1 Antiviral compositions VERRECK GEERT 2006-06-15 US disclosed
US-20060128733-A1 Method for treating HIV infection through co-administration of tipranavir and reverset BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-06-15 US disclosed
EP-1668011-A2 HIV REPLICATION INHIBITING PURINE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2006-06-14 EP disclosed
WO-2006060177-A1 METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND GW873140 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-06-08 WO disclosed
WO-2006060159-A1 METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND GW695634 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-06-08 WO disclosed
WO-2006060175-A1 METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND SCH-417690 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-06-08 WO disclosed
US-20060122220-A1 Method for treating HIV infection through co-administration of tipranavir and UK-427,857 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-06-08 US disclosed
WO-2006055455-A1 METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND DARUNAVIR BOEHRINGER INGELHEIM INTERNATIONAL, GMBH (DE) 2006-05-26 WO disclosed
WO-2006055660-A2 METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND UK-427, 857 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-05-26 WO disclosed
WO-2006055754-A1 METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND REVERSET BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-05-26 WO disclosed
US-20060111379-A1 Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino] benzonitrile JANSSEN PHARMACEUTICA N.V. (BE) 2006-05-25 US disclosed
WO-2006052373-A2 METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND ETRAVIRINE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-05-18 WO disclosed
US-20060106043-A1 Method for treating HIV infection through co-administration of tipranavir and etravirine BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-05-18 US disclosed
WO-2006045828-A1 HIV INHIBITING BICYCLIC PYRIMIDINE DERIVATIVES TIBOTEC PHARMACEUTICALS LTD. (IE) 2006-05-04 WO disclosed
US-7037917-B2 HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICA, N.V. (BE) 2006-05-02 US disclosed
US-7034019-B2 Prodrugs of HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICA N.V. (BE) 2006-04-25 US disclosed
WO-2006035067-A2 HIV INHIBITING 5-HETEROCYCLYL PYRIMIDINES TIBOTEC PHARMACEUTICALS LTD. (IE) 2006-04-06 WO disclosed
WO-2006035069-A1 HIV INHIBITING 5-SUBSTITUTED PYRIMIDINES TIBOTEC PHARMACEUTICALS LTD. (IE) 2006-04-06 WO disclosed
WO-2006035068-A2 HIV INHIBITING 5-CARBO- OR HETEROCYCLIC SUBSTITUTED PYRIMIDINES TIBOTEC PHARMACEUTICALS LTD. (IE) 2006-04-06 WO disclosed
US-7015221-B2 2,4-disubstituted triazine derivatives JANSSEN PHARMACEUTICA, N.V. (BE) 2006-03-21 US disclosed
US-20060049177-A1 Induction heating cooker LG ELECTRONICS INC. 2006-03-09 US disclosed
WO-2006024668-A1 HYDROCHLORIDE OF 4-[[4-[[4-(2-CYANOETHENYL)-2,6-DIMETHYLPHENYL]AMINO]-2-PYRIMIDINYL] AMINO]BENZONITRILE JANSSEN PHARMACEUTICA N.V. (BE) 2006-03-09 WO disclosed
WO-2006024667-A1 FURAMATE OF 4-( (4-( (4- (2-CYANOETHENYL) -2,6-DIMETHYLPHENYL)AMINO)-2-PYRIMIDINYL)AMINO)BENZONITRILE JANSSEN PHARMACEUTICA N.V. (BE) 2006-03-09 WO disclosed
EP-1632232-A1 Salt of 4-[[4-[[4-(2-Cyanoethenyl)-2,6-dimethylphenyl]amino]-2-Pyrimidinyl]amino]benzonitrile JANSSEN PHARMACEUTICA N.V. (BE) 2006-03-08 EP disclosed
WO-2006015985-A1 HIV INHIBITING 1,2,4-TRIAZIN-6-ONE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2006-02-16 WO disclosed
EP-1225874-B1 ANTIVIRAL SOLID DISPERSIONS JANSSEN PHARMACEUTICA NV (BE) 2006-02-01 EP disclosed
US-20060009474-A1 Prodrugs of HIV replication inhibiting pyrimidines KUKLA MICHAEL J 2006-01-12 US disclosed
EP-1129079-B1 2,4-DISUBSTITUDED TRIAZINE DERIVATIVES WITH ANTI HIV ACTIVITY JANSSEN PHARMACEUTICA NV (BE) 2006-01-04 EP disclosed
US-20050288278-A1 HIV replication inhibiting pyrimidines CORTE BART DE 2005-12-29 US disclosed
US-20050277641-A1 2,4-DISUBSTITUTED TRIAZINE DERIVATIVES JANSSEN PHARMACEUTICA, N.V. 2005-12-15 US disclosed
EP-1597237-A1 PYRIMIDINE DERIVATIVES FOR THE PREVENTION OF HIV INFECTION JANSSEN PHARMACEUTICA N.V. (BE) 2005-11-23 EP disclosed
US-6962916-B2 Substituted diamino-1,3,5-triazine derivatives JANSSEN PHARMACEUTICA N.V. (BE) 2005-11-08 US disclosed
US-20050197354-A1 4-[[4-[(2,6-dichloro-phenyl)methyl]-6-[[2-(1-pyrrolidinyl)ethyl]amino]-2-pyrimidinyl]amino]benzonitrile; 4-[[4-[(2,4,6-trimethylphenyl)amino]-2-pyrimidinyl]amino]benzamide, N1-oxide combined with another retrovirus inhibitor; viricides; treatment of AIDS ANDRIES KOENRAAD JOZEF L M (BE) 2005-09-08 US disclosed
US-20050192305-A1 HIV inhibiting pyrimidine derivatives ANDRIES KOENRAAD JOZEF L M (BE) 2005-09-01 US disclosed
CN-1214013-C HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICA NV (BE) 2005-08-10 CN disclosed
CN-1207290-C 2, 4-disubstituted triazine derivatives JANSSEN PHARMACEUTICA NV (BE) 2005-06-22 CN disclosed
US-6903213-B2 HIV inhibiting pyrimidine derivatives ANDRIES KOENRAAD JOZEF LODEWIJ (BE) 2005-06-07 US disclosed
EP-1066269-B1 TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS JANSSEN PHARMACEUTICA NV (BE) 2005-05-11 EP disclosed
US-6878717-B2 HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICA, N.V. (BE) 2005-04-12 US disclosed
WO-2005028479-A2 HIV REPLICATION INHIBITING PURINE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2005-03-31 WO disclosed
US-6858609-B2 Substituted diamino-1,3,5-triazine derivatives JANSSEN PHARMACEUTICA N.V. (BE) 2005-02-22 US disclosed
EP-1505980-A1 MICROBICIDAL PYRIMIDINE OR TRIAZINE FOR PREVENTING SEXUAL HIV TRANSMISSION Tibotec Pharmaceuticals Ltd. (IE) 2005-02-16 EP disclosed
US-20040229847-A1 Pyridinone and pyridinethione derivatives having hiv inhibiting properties CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2004-11-18 US disclosed
US-20040198739-A1 Prevention reproduction of virus JANSSEN PHARMACEUTICA N.V. (BE) 2004-10-07 US disclosed
WO-2004069812-A1 PYRIMIDINE DERIVATIVES FOR THE PREVENTION OF HIV INFECTION JANSSEN PHARMACEUTICA N.V. (BE) 2004-08-19 WO disclosed
US-6774235-B2 HAVING HIV REPLICATION INHIBITING PROPERTIES. JANSSEN PHARMACEUTICA N.V. (BE) 2004-08-10 US disclosed
US-20040102456-A1 Hiv inhibiting pyrazinone derivatives K. U. LEUVEN RESEARCH & DEVELOPMENT (BE) 2004-05-27 US disclosed
EP-1419152-A1 HIV INHIBITING PYRIMIDINES DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2004-05-19 EP disclosed
EP-0834507-B1 Substituted diamino-1,3,5-triazine derivatives JANSSEN PHARMACEUTICA NV (BE) 2004-05-19 EP disclosed
US-20040039005-A1 Nitrogen compounds such as 4-((4-amino-5-bromo-6-(4-cyano-2,6-dimethylphenyloxy)-2 -pyrimidinyl)amino)benzonitrile, used as protease inhibitors for prophylaxis of viral diseases JANSSEN PHARMACEUTICA N.V. (BE) 2004-02-26 US disclosed
EP-1370265-A1 HIV INHIBITING PYRAZINONE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2003-12-17 EP disclosed
WO-2003094920-A1 MICROBICIDAL PYRIMIDINE OR TRIAZINE FOR PREVENTING SEXUAL HIV TRANSMISSION TIBOTEC PHARMACEUTICALS LTD (IE) 2003-11-20 WO disclosed
US-20030199473-A1 Substituted diamino-1,3,5-triazine derivatives JANSSEN PHARMACEUTICA N.V. 2003-10-23 US disclosed
US-20030186990-A1 Prodrugs of hiv replication inhibiting pyrimidines JANSSEN PHARMACEUTICA, INC. 2003-10-02 US disclosed
US-20030171374-A1 HIV replication inhibitors JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2003-09-11 US disclosed
EP-0945443-B9 HIV inhibiting pyrimidine derivatives JANSSEN PHARMACEUTICA NV (BE) 2003-08-13 EP disclosed
US-20030114472-A1 Viricides JANSSEN PHARMACEUTICA, N.V. (BE) 2003-06-19 US disclosed
EP-1318995-A2 PYRIDINONE AND PYRIDINETHIONE DERIVATIVES HAVING HIV INHIBITING PROPERTIES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2003-06-18 EP disclosed
US-20030083317-A1 HIV inhibiting pyrimidine derivatives ANDRIES KOENRAAD JOZEF LODEWIJ (BE) 2003-05-01 US disclosed
EP-1002795-B1 HIV Replication inhibiting pyrimidines JANSSEN PHARMACEUTICA NV (BE) 2003-03-05 EP disclosed
WO-2003016306-A1 HIV INHIBITING PYRIMIDINES DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2003-02-27 WO disclosed
EP-1282607-A2 PRODRUGS OF HIV REPLICATION INHIBITING PYRIMIDINES JANSSEN PHARMACEUTICA N.V. (BE) 2003-02-12 EP disclosed
EP-0945443-B1 HIV inhibiting pyrimidine derivatives JANSSEN PHARMACEUTICA NV (BE) 2003-02-12 EP disclosed
EP-1270560-A1 Hiv replication inhibiting pyrimidines JANSSEN PHARMACEUTICA N.V. (BE) 2003-01-02 EP disclosed
WO-2002078708-A1 HIV INHIBITING PYRAZINONE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 2002-10-10 WO disclosed
US-20020147181-A1 Substituted diamino-1,3,5-triazine derivatives JANSSEN PAUL A J (BE) 2002-10-10 US disclosed
EP-1245567-A1 HIV inhibiting pyrimidine derivatives JANSSEN PHARMACEUTICA N.V. (BE) 2002-10-02 EP disclosed
US-6440986-B2 VIRICIDES JANSSEN PHARMACEUTICA, N.V. (BE) 2002-08-27 US disclosed
US-20020115668-A1 Trisubstituted 1,3,5-triazine derivatives DAEYAERT FREDERIK FRANS DESIRE (BE) 2002-08-22 US disclosed
EP-1225874-A1 ANTIVIRAL COMPOSITIONS Janssen Pharmaceutica N.V. (BE) 2002-07-31 EP disclosed
US-6380194-B1 FOR TREATMENT OF SUBJECTS SUFFERING FROM HIV INFECTION JANSSEN PHARMACEUTICA N.V. (BE) 2002-04-30 US disclosed
US-6372729-B1 TREATMENT OF VIRAL DISEASES SUCH AS AIDS JANSSEN PHARMACEUTICA N.V. (BE) 2002-04-16 US disclosed
WO-2002024650-A2 PYRIDINONE AND PYRIDINETHIONE DERIVATIVES HAVING HIV INHIBITING PROPERTIES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2002-03-28 WO disclosed
CN-1325387-A 2,4-disubstituted triazine derivatives JANSSEN PHARMACEUTICA NV (BE) 2001-12-05 CN disclosed
WO-2001085699-A2 PRODRUGS OF HIV REPLICATION INHIBITING PYRIMIDINES JANSSEN PHARMACEUTICA N.V. (BE) 2001-11-15 WO disclosed
CN-1322198-A HIV replication inhibiting pyrimidines JANSSEN PHARMACEUTICA NV (BE) 2001-11-14 CN disclosed
EP-1129079-A2 2,4-DISUBSTITUDED TRIAZINE DERIVATIVES WITH ANTI HIV ACTIVITY Janssen Pharmaceutica N.V. (BE) 2001-09-05 EP disclosed
US-20010011094-A1 HIV inhibiting pyrimidine derivatives ANDRIES KOENRAAD JOZEF LODEWIJ (BE) 2001-08-02 US disclosed
WO-2001022938-A1 ANTIVIRAL COMPOSITIONS JANSSEN PHARMACEUTICA N.V. (BE) 2001-04-05 WO disclosed
US-6197779-B1 VIRICIDE JANSSEN PHARMACEUTICA, INC. 2001-03-06 US disclosed
US-6150360-A ADMINISTERING TO A PATIENT SUFFERING FROM HUMAN IMMUNODEFICIENCY VIRUS INFECTION A TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVE JANSSEN PHARMACEUTICA N.V. (BE) 2000-11-21 US disclosed
EP-1002795-A1 HIV Replication inhibiting pyrimidines JANSSEN PHARMACEUTICA N.V. (BE) 2000-05-24 EP disclosed
WO-2000027828-A2 2,4-DISUBSTITUTED TRIAZINE DERIVATIVES WITH ANTI HIV ACTIVITY JANSSEN PHARMACEUTICA N.V. (BE) 2000-05-18 WO disclosed
WO-2000027825-A1 HIV REPLICATION INHIBITING PYRIMIDINES JANSSEN PHARMACEUTICA N.V. (BE) 2000-05-18 WO disclosed
WO-1999050250-A1 HIV INHIBITING PYRIMIDINE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 1999-10-07 WO disclosed
EP-0945443-A1 HIV inhibiting pyrimidine derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1999-09-29 EP disclosed
EP-0945442-A1 Trisubstituted pyrimidine derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1999-09-29 EP disclosed
EP-0945447-A1 Trisubstituted 1,3,5-triazine derivatives for treatment of HIV infections JANSSEN PHARMACEUTICA N.V. (BE) 1999-09-29 EP disclosed
US-5948786-A BLOCKING TUMOR NECROSIS FACTOR SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1999-09-07 US disclosed
EP-0684818-B1 METHOD OF REVERSING RESISTANCE OF HIV-1 STRAINS TO ZIDOVUDINE JANSSEN PHARMACEUTICA NV (BE) 1999-05-06 EP disclosed
EP-0834507-A1 Substituted diamino-1,3,5-triazine derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1998-04-08 EP disclosed
US-5684049-A HIV-inhibiting benzeneacetamide derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1997-11-04 US disclosed
EP-0538301-B1 HIV-INHIBITING BENZENEACETAMIDE DERIVATIVES JANSSEN PHARMACEUTICA NV (BE) 1996-10-30 EP disclosed
US-5556886-A VIRICIDES JANSSEN PHARMACEUTICA N.V. (BE) 1996-09-17 US disclosed
EP-0684818-A1 METHOD OF REVERSING RESISTANCE OF HIV-1 STRAINS TO ZIDOVUDINE JANSSEN PHARMACEUTICA N.V. (BE) 1995-12-06 EP disclosed
CN-1107835-A A process for preparing pharmaceutical composition showing properties in against human immunodeficiency virus JANSSEN PHARMACEUTICA NV (BE) 1995-09-06 CN disclosed
EP-0666744-A1 USE OF BHAP COMPOUNDS IN COMBINATION WITH OTHER NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS FOR THE TREATMENT OF HIV INFECTION THE UPJOHN COMPANY (US) 1995-08-16 EP disclosed
CN-1028990-C Process for preparing phenylacetamide derivatives for inhibiting human immunodeficiency virus JANSSEN PHARMACEUTICA NV (BE) 1995-06-21 CN disclosed
WO-1994018963-A1 METHOD OF REVERSING RESISTANCE OF HIV-1 STRAINS TO ZIDOVUDINE JANSSEN PHARMACEUTICA N.V. (BE) 1994-09-01 WO disclosed
WO-1994009781-A1 USE OF BHAP COMPOUNDS IN COMBINATION WITH OTHER NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS FOR THE TREATMENT OF HIV INFECTION THE UPJOHN COMPANY (US) 1994-05-11 WO disclosed
EP-0538301-A1 HIV-INHIBITING BENZENEACETAMIDE DERIVATIVES. JANSSEN PHARMACEUTICA NV (BE) 1993-04-28 EP disclosed
CN-1058958-A HIV inhibiting phenylacetamide derivatives JANSSEN PHARMACEUTICA NV (BE) 1992-02-26 CN disclosed
WO-1992000952-A1 HIV-INHIBITING BENZENEACETAMIDE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 1992-01-23 WO disclosed
WO-1992000952-A1 HIV-INHIBITING BENZENEACETAMIDE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 1992-01-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (50 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115668-A1 Trisubstituted 1,3,5-triazine derivatives XDH, CCR5, CXCR1 MAPT 4642/4885L3MBTL1 1702/4885MAPK1 1044/4885
US-20200345733-A1 Microbicidal Pyrimidine or Triazine Containing Compounds SAMHD1, NT5C2, TK1 MAPT 3289/4885L3MBTL1 3001/4885MAPK1 3314/4885
US-20200069579-A1 DISPERSIBLE COMPOSITIONS VPS35, RAB35, RAB6A MAPT 478/4885L3MBTL1 3932/4885MAPK1 2014/4885
US-20030199473-A1 Substituted diamino-1,3,5-triazine derivatives CCR1, CCR6, CCR5 MAPT 3470/4885L3MBTL1 2697/4885MAPK1 826/4885
US-20090012092-A1 Hiv Inhibiting 1,2,4-Triazin-6-One Derivatives NCOR1, NR1H3, NCOA3 MAPT 4232/4885L3MBTL1 740/4885MAPK1 1804/4885
US-20140343006-A1 HIV Replication Inhibiting Pyrimidines RRM2B, CCNO, RRM2 MAPT 4242/4885L3MBTL1 539/4885MAPK1 2888/4885
US-20170121292-A1 HIV REPLICATION INHIBITING PYRIMIDINES RRM2B, CCNO, RRM2 MAPT 4242/4885L3MBTL1 539/4885MAPK1 2888/4885
US-20020147181-A1 Substituted diamino-1,3,5-triazine derivatives CCR1, CCR6, CCR5 MAPT 3230/4885L3MBTL1 2352/4885MAPK1 1074/4885
US-20060135563-A1 Method for treating HIV infection through co-administration of tipranavir and SCH-417690 SAMHD1, VPS51, CCR5 MAPT 227/4885L3MBTL1 2440/4885MAPK1 4267/4885
US-20220008333-A1 DISPERSIBLE COMPOSITIONS VPS35, RAB35, RAB6A MAPT 478/4885L3MBTL1 3932/4885MAPK1 2014/4885
US-20070021449-A1 Pyrimidine derivatives for the prevention of hiv infection ADORA2B, CYP1B1, DPYD MAPT 3887/4885L3MBTL1 3825/4885MAPK1 922/4885
US-20090012108-A1 SALT OF 4-[[4-[[4-(2-CYANOETHENYL)-2,6-DIMETHYLPHENYL]AMINO]-2-PYRIMIDINYL]AMINO]BENZONITRILE CLIC4, HCN4, SCN4A MAPT 993/4885L3MBTL1 4835/4885MAPK1 1420/4885
US-20030083317-A1 HIV inhibiting pyrimidine derivatives CBR1, CCR1, CXCR1 MAPT 4593/4885L3MBTL1 1853/4885MAPK1 816/4885
US-20070196478-A1 ANTIVIRAL COMPOSITIONS EIF2AK2, ZC3HAV1, RPL35 MAPT 879/4885L3MBTL1 1961/4885MAPK1 3898/4885
US-20080176880-A1 Activity against strains having acquired resistance nonnucleoside reverse transcriptase inhibitors; human alpha1 acid glycoprotein nonbinding; such as 4-[[(5-bromo-4,6-dichloro)-2-pyrimidinyl]amino]-benzonitrile ABCC1, MGAT1, RRM2 MAPT 4585/4885L3MBTL1 318/4885MAPK1 3177/4885
US-20190322628-A1 HIV REPLICATION INHIBITING PYRIMIDINES RRM2B, CCNO, RRM2 MAPT 4242/4885L3MBTL1 539/4885MAPK1 2888/4885
US-11065198-B2 Dispersible compositions VPS35, RAB35, RAB6A MAPT 478/4885L3MBTL1 3932/4885MAPK1 2014/4885
US-20030114472-A1 Viricides ZC3HAV1, ZC3HAV1L, POLR2H MAPT 4504/4885L3MBTL1 186/4885MAPK1 3738/4885
US-20080262007-A1 Hiv Inhibiting 5-Substituted Pyrimidines CBR1, RCOR1, CBR3 MAPT 3851/4885L3MBTL1 1178/4885MAPK1 1114/4885
US-20050192305-A1 HIV inhibiting pyrimidine derivatives NR4A1, CCR5, NR4A3 MAPT 4739/4885L3MBTL1 2534/4885MAPK1 2881/4885
US-20060142344-A1 Method for treating HIV infection through co-administration of tipranavir and GW695634 TIPARP, CD4, HDLBP MAPT 556/4885L3MBTL1 1375/4885MAPK1 3611/4885
US-20170100399-A1 Microbicidal Pyrimidine Or Triazine Containing Compounds SAMHD1, NT5C2, TK1 MAPT 3375/4885L3MBTL1 2973/4885MAPK1 3393/4885
US-10611732-B2 HIV replication inhibiting pyrimidines RRM2B, CCNO, RRM2 MAPT 4242/4885L3MBTL1 539/4885MAPK1 2888/4885
US-20040102456-A1 Hiv inhibiting pyrazinone derivatives SUB1, CCR5, CCR6 MAPT 4660/4885L3MBTL1 1741/4885MAPK1 483/4885
US-20080167296-A1 1,5,6,-Substituted-2-Oxo-3-Cyano-1,6a-Diaza-Tetrahydro-Fluoranthenes as Anti-Infective Agents CYP2A7, CYP3A7, NEK7 MAPT 4836/4885L3MBTL1 1488/4885MAPK1 2635/4885
US-20180009819-A1 HIV INHIBITING BICYCLIC PYRIMIDINE DERIVATIVES COX6C, ZC3HAV1L, RRM2B MAPT 4074/4885L3MBTL1 18/4885MAPK1 2969/4885
US-20010011094-A1 HIV inhibiting pyrimidine derivatives CBR1, CCR1, NR4A1 MAPT 4564/4885L3MBTL1 1979/4885MAPK1 676/4885
US-20080214588-A1 Hiv Inhibiting 2-(4-Cyanophenyl)-6-Hydroxylaminopyrimidines RTF2, MCM6, SAMHD1 MAPT 2365/4885L3MBTL1 654/4885MAPK1 2182/4885
US-10072015-B2 HIV inhibiting bicyclic pyrimidine derivatives ZC3HAV1, CCR6, ZC3HAV1L MAPT 4285/4885L3MBTL1 19/4885MAPK1 2737/4885
US-20110263625-A1 HIV REPLICATION INHIBITING PYRIMIDINES NSUN2, CCNO, POLR2H MAPT 4408/4885L3MBTL1 155/4885MAPK1 2725/4885
US-20120076835-A1 HIV INHIBITING PYRIMIDINES DERIVATIVES TYMS, PNP, DUT MAPT 989/4885L3MBTL1 3637/4885MAPK1 1216/4885
US-20080085907-A1 Hiv Inhibiting Bicyclic Pyrimdine Derivatives CCR6, CD4, CCNT1 MAPT 4148/4885L3MBTL1 37/4885MAPK1 2785/4885
US-20060160859-A1 Method for treating HIV infection through co-administration of tipranavir and GW873140 NAA40, TRIM25, CD4 MAPT 704/4885L3MBTL1 1044/4885MAPK1 1763/4885
US-20050197354-A1 4-[[4-[(2,6-dichloro-phenyl)methyl]-6-[[2-(1-pyrrolidinyl)ethyl]amino]-2-pyrimidinyl]amino]benzonitrile; 4-[[4-[(2,4,6-trimethylphenyl)amino]-2-pyrimidinyl]amino]benzamide, N1-oxide combined with another retrovirus inhibitor; viricides; treatment of AIDS HAVCR2, CBR1, NR4A1 MAPT 4813/4885L3MBTL1 263/4885MAPK1 4276/4885
US-20050288278-A1 HIV replication inhibiting pyrimidines NSUN2, POLR2H, CCNO MAPT 4304/4885L3MBTL1 105/4885MAPK1 2260/4885
US-20180244632-A1 HIV REPLICATION INHIBITING PYRIMIDINES RRM2B, CCNO, RRM2 MAPT 4242/4885L3MBTL1 539/4885MAPK1 2888/4885
US-20070037811-A1 HIV replication inhibitors; for (multi)drug resistant HIV infection REV1, CCNI, MCM6 MAPT 1796/4885L3MBTL1 2507/4885MAPK1 2209/4885
US-20160355519-A1 HIV INHIBITING BICYCLIC PYRIMIDINE DERIVATIVES COX6C, ZC3HAV1L, RRM2B MAPT 4167/4885L3MBTL1 21/4885MAPK1 3034/4885
US-20180016281-A1 HIV INHIBITING BICYCLIC PYRIMIDINE DERIVATIVES COX6C, ZC3HAV1L, CCR6 MAPT 4087/4885L3MBTL1 14/4885MAPK1 2995/4885
US-20100034810-A1 PYRIMIDINE DERIVATIVES FOR THE PREVENTION OF HIV INFECTION NOX3, CBR3, CBR1 MAPT 4688/4885L3MBTL1 1435/4885MAPK1 3202/4885
US-20110008434-A1 SALT OF 4-[[4-[[4-(2-CYANOETHENYL)-2,6-DIMETHYLPHENYL]AMINO]-2-PYRIMIDINYL]AMINO]BENZONITRILE CLIC4, HCN4, SCN4A MAPT 993/4885L3MBTL1 4835/4885MAPK1 1420/4885
US-20060135562-A1 Method for treating HIV infection through co-administration of tipranavir and darunavir SAMHD1, DARS1, APOBEC3A MAPT 283/4885L3MBTL1 2975/4885MAPK1 4701/4885
US-20110165093-A1 MICROBICIDAL PYRIMIDINE OR TRIAZINE FOR PREVENTING SEXUAL HIV TRANSMISSION SAMHD1, NT5C2, TPMT MAPT 3154/4885L3MBTL1 3345/4885MAPK1 3038/4885
US-20180116964-A1 SALT OF 4-[[4-[[4-(2-CYANOETHENYL)-2,6-DIMETHYLPHENYL]AMINO]-2-PYRIMIDINYL]AMINO]BENZONITRILE SCN4A, PKD1, AFF4 MAPT 724/4885L3MBTL1 4791/4885MAPK1 1952/4885
US-20110150996-A1 SALT OF 4-[[4-[[4-(2-CYANOETHENYL)-2,6-DIMETHYLPHENYL]AMINO] -2-PYRIMIDINYL]AMINO]BENZONITRILE SCN4A, PKD1, AFF4 MAPT 724/4885L3MBTL1 4791/4885MAPK1 1952/4885
US-20080194602-A1 Hiv Inhibiting 2-(4-Cyanophenylamino) Pyrimidine Oxide Derivatives RTF2, SAMHD1, NUDT1 MAPT 2856/4885L3MBTL1 979/4885MAPK1 1262/4885
US-20040229847-A1 Pyridinone and pyridinethione derivatives having hiv inhibiting properties CYP2B6, CYP2S1, CYP2D6 MAPT 4015/4885L3MBTL1 3774/4885MAPK1 916/4885
US-20120190697-A1 HIV INHIBITING BICYCLIC PYRIMIDINE DERIVATIVES ZC3HAV1, CCR6, COX6C MAPT 4320/4885L3MBTL1 17/4885MAPK1 2786/4885
US-10077270-B2 HIV inhibiting bicyclic pyrimidine derivatives ZC3HAV1, CCR6, COX6C MAPT 4320/4885L3MBTL1 17/4885MAPK1 2786/4885
US-20060106043-A1 Method for treating HIV infection through co-administration of tipranavir and etravirine TMPRSS4, CYP3A7, CYP3A4 MAPT 208/4885L3MBTL1 3213/4885MAPK1 4482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.