Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 18/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 18/20 | 0.60 |
| ▸ | PIK3CG | P48736 | 18/20 | 0.60 |
| ▸ | PRKDC | P78527 | 18/20 | 0.60 |
| ▸ | ABL1 | P00519 | 2/20 | 0.54 |
| ▸ | SRC | P12931 | 2/20 | 0.54 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.51 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.51 |
| ▸ | ADK | P55263 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | HCK | P08631 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322473 | 0.82 | ABL1 (0.40) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL8326897 | 0.75 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL8975546 | 0.75 | ADK (0.50) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL30387566 | 0.73 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL2905037 | 0.71 | PIK3CD (0.60) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL8684518 | 0.70 | ILK (0.50) | KDR | |
| SCHEMBL30124898 | 0.69 | STK4 (0.61) | ABL1ADKKDR | |
| SCHEMBL18493857 | 0.68 | PIK3CD (0.56) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL14414209 | 0.67 | MAP4K4 (0.63) | ABL1ADKKDR | |
| SCHEMBL1850197 | 0.67 | PIK3CD (0.55) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506347-A | ADENOSINE KINASE INHIBITOR | GENSIA, INC. (US) | 1996-04-09 | — | — | US | disclosed |