Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | YARS1 | P54577 | 2/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975669 | 1.00 | SLC7A5 (0.60) | SLC7A5MMP2YARS1ERAP2LNPEP | |
| SCHEMBL10974111 | 1.00 | SLC7A5 (0.60) | SLC7A5MMP2YARS1ERAP2LNPEP | |
| SCHEMBL11023209 | 0.90 | OPRD1 (0.53) | SLC7A5MMP2OPRD1OPRM1OPRK1 | |
| SCHEMBL11358086 | 0.90 | OPRD1 (0.53) | SLC7A5MMP2OPRD1OPRM1OPRK1 | |
| SCHEMBL2182117 | 0.89 | OPRD1 (0.64) | SLC7A5YARS1OPRD1OPRM1OPRK1 | |
| SCHEMBL583171 | 0.87 | ALPI (0.58) | SLC7A5MMP2 | |
| SCHEMBL583172 | 0.87 | ALPI (0.58) | SLC7A5MMP2 | |
| SCHEMBL11406587 | 0.87 | OPRD1 (0.50) | SLC7A5YARS1ERAP2OPRD1OPRM1 | |
| SCHEMBL6019626 | 0.86 | CTSL (0.59) | SLC7A5MMP2YARS1ERAP2LNPEP | |
| SCHEMBL10975699 | 0.85 | MMP2 (0.53) | SLC7A5MMP2YARS1ERAP2LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436660-B1 | PEPTIDES AND ANTIBODIES THAT INHIBIT INTEGRIN-LIGAND BINDING | SCRIPPS RESEARCH INST (US) | 1996-04-17 | — | — | EP | disclosed |
| US-5204445-A | PEPTIDES AND ANTIBODIES THAT INHIBIT INTEGRIN-LIGAND BINDING | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-04-20 | — | — | US | disclosed |
| US-5149780-A | 60 to 90 amino acid residues in length, ability to prevent receptor mediated cell adhesion such as aggregation of platelets and fibroblasts to a matrix | THE SCRIPPS RESEARCH INSTITUTE (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0436660-A4 | PEPTIDES AND ANTIBODIES THAT INHIBIT INTEGRIN-LIGAND BINDING | — | 1992-02-12 | — | — | EP | disclosed |
| EP-0436660-A1 | PEPTIDES AND ANTIBODIES THAT INHIBIT INTEGRIN-LIGAND BINDING. | SCRIPPS CLINIC RES (US) | 1991-07-17 | — | — | EP | disclosed |
| WO-1990003983-A1 | PEPTIDES AND ANTIBODIES THAT INHIBIT INTEGRIN-LIGAND BINDING | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1990-04-19 | — | — | WO | disclosed |