Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975682 | 0.84 | CA1 (0.50) | CA4CA12CA1CA2CA7 | |
| SCHEMBL2789100 | 0.80 | CHAT (0.49) | CA1CA2TSHRPOLBKDM4E | |
| SCHEMBL5027103 | 0.77 | IRAK4 (0.40) | CA4CA12CA1CA2CA7 | |
| SCHEMBL563510 | 0.76 | APP (0.55) | TSHRKDM4EALDH1A1SMN1; SMN2GRM5 | |
| SCHEMBL3950311 | 0.74 | SMN1; SMN2 (0.42) | CA4CA12CA1CA2CA7 | |
| SCHEMBL28486164 | 0.69 | CYP1A2 (0.59) | ALDH1A1SMN1; SMN2MAPK1GRM5APP | |
| SCHEMBL6364807 | 0.67 | CYP1A2 (0.46) | TSHRKDM4EALDH1A1SMN1; SMN2APP | |
| SCHEMBL1639958 | 0.67 | GRM5 (0.32) | CA4CA12CA1CA2CA7 | |
| SCHEMBL3956017 | 0.65 | KDM4E (0.33) | TSHRKDM4EALDH1A1GRM5MEN1 | |
| SCHEMBL7983223 | 0.65 | APP (0.48) | KDM4EALDH1A1SMN1; SMN2GRM5APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008471-A | Process for the preparation of rooperol | ROOPEROL (N.A.) (NL) | 1991-04-16 | — | — | US | disclosed |
| EP-0206765-B1 | PROCESS FOR PREPARATION OF ROOPEROL, HYPOXOSIDE AND DERIVATIVES THEREOF | ROOPEROL (NA) NV (NL) | 1991-03-06 | — | — | EP | disclosed |
| US-4956502-A | Process for the preparation of rooperol derivative | ROOPEROL (N.A.) NV (AN) | 1990-09-11 | — | — | US | disclosed |
| EP-0206765-A2 | Process for preparation of rooperol, hypoxoside and derivatives thereof | ROOPEROL (NA) NV (NL) | 1986-12-30 | — | — | EP | disclosed |