Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL8975799

CO[n+]1ccc2c(c1)c1cc([Sn](C)(C)C)ccc1n2C.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.35

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HSP90AA1 P07900 1/20 0.31
G6PD P11413 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL8975730 0.93 BCHE (0.40) BCHEACHEKDM4EMEN1ALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL8976223 0.81 ACHE (0.50) BCHEACHEMAPT
Trifluoromethanesulfonic Acid SCHEMBL8976067 0.76 NSD2 (0.34) HSP90AA1
Trifluoromethanesulfonic Acid SCHEMBL8976385 0.75
SCHEMBL8975697 0.73 BCHE (0.37) BCHEACHEKDM4EMEN1ALDH1A1
SCHEMBL8976156 0.68 ACHE (0.43) BCHEACHEKDM4EMEN1ALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL9849403 0.65 KCNH2 (0.43) ACHE
Trifluoromethanesulfonic Acid SCHEMBL8975675 0.64 ACHE (0.37) BCHEACHEKDM4EMEN1ALDH1A1
SCHEMBL8976154 0.61 MAPT (0.33) BCHEACHEKDM4EMEN1ALDH1A1
SCHEMBL8975983 0.59 MAOA (0.43) ACHEKDM4EMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5532261-A TREATING STAPHYLOCOCCUS INFECTIONS MERCK & CO., INC. (US) 1996-07-02 US disclosed