Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976111 | 0.89 | ADORA3 (0.43) | MAOAMAOBTOP2AACHEADORA3 | |
| SCHEMBL280029 | 0.80 | TOP2A (0.50) | MAOAMAOBTOP2AACHEADORA3 | |
| SCHEMBL13100687 | 0.78 | ACHE (0.49) | MAOAMAOBTOP2AACHEADORA3 | |
| SCHEMBL8975963 | 0.77 | MAOA (0.44) | MAOAMAOBTOP2AACHEADORA3 | |
| SCHEMBL9968105 | 0.75 | MAOA (0.43) | MAOAMAOBTOP2AACHETUBB4A | |
| SCHEMBL2628358 | 0.73 | ADORA3 (0.49) | MAOAMAOBTOP2AACHEADORA3 | |
| SCHEMBL16625725 | 0.73 | ATM (0.48) | MAOAMAOBTOP2AACHECYP2D6 | |
| SCHEMBL8975764 | 0.72 | FEN1 (0.40) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL29548306 | 0.72 | GPR3 (0.64) | MAOAMAOBTOP2AACHECYP2D6 | |
| SCHEMBL280028 | 0.72 | GPR3 (0.64) | MAOAMAOBTOP2AACHECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532261-A | TREATING STAPHYLOCOCCUS INFECTIONS | MERCK & CO., INC. (US) | 1996-07-02 | — | — | US | disclosed |