Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975448 | 0.87 | TAS1R3 (0.37) | TAS1R3TAS1R1ALOX5MEN1NR1I2 | |
| SCHEMBL8883577 | 0.84 | TAS1R3 (0.36) | TAS1R3TAS1R1ALOX5MEN1NR1I2 | |
| SCHEMBL8883095 | 0.83 | TAS1R3 (0.35) | TAS1R3TAS1R1ALOX5MEN1NR1I2 | |
| SCHEMBL1897757 | 0.82 | ALDH1A1 (0.40) | TAS1R3TAS1R1TACR3PLA2G2C | |
| SCHEMBL31373087 | 0.82 | ALDH1A1 (0.40) | TAS1R3TAS1R1TACR3PLA2G2C | |
| SCHEMBL8885183 | 0.80 | SMN1; SMN2 (0.43) | TAS1R3TAS1R1ALOX5MEN1CYP3A4 | |
| SCHEMBL3957281 | 0.76 | CHEK1 (0.36) | TAS1R3TAS1R1TACR3 | |
| SCHEMBL4313304 | 0.76 | TACR3 (0.41) | TAS1R3TAS1R1ALOX5KMT2ATACR3 | |
| SCHEMBL3623844 | 0.74 | TACR3 (0.37) | TAS1R3TAS1R1ALOX5KMT2ATACR3 | |
| SCHEMBL4551477 | 0.72 | GLA (0.43) | TAS1R3TAS1R1ALOX5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508137-A | REACTING A PERYLENE-3,4:9,10-TETRACARBOXYLIC MONOANHYDRIDE MONOIMIDE WITH A PRIMARY DIAMINE; FLUORESCENT DYE IN CHEMILUMINESCENCE SYSTEMS | CIBA-GEIGY CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |