SCHEMBL897593

SCHEMBL897593

Oc1cc(Cl)ccc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL91153 0.79
SCHEMBL29629596 0.79
SCHEMBL28686760 0.77 ALOX15 (0.54)
SCHEMBL28700548 0.77 ALOX15 (0.54)
SCHEMBL28708943 0.77 ALOX15 (0.54)
SCHEMBL19600443 0.75 CXCR2 (0.46)
SCHEMBL25408639 0.75 HSD17B10 (0.46)
SCHEMBL7814426 0.75
SCHEMBL30030367 0.75
SCHEMBL339112 0.75 HSD17B10 (0.65)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 424 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12522597-B2 Methods and compositions for modulating splicing SKYHAWK THERAPEUTICS, INC. (US) 2026-01-13 US disclosed
US-12503459-B2 Light emitting device and amine compound for the same SAMSUNG DISPLAY CO., LTD. (KR) 2025-12-23 US disclosed
EP-4660194-A1 SALT AND CRYSTAL FORM OF CYCLOALKENE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) 2025-12-10 EP disclosed
US-12471490-B2 Organic compound, organic light-emitting diode including organic compound, and display device including organic light-emitting diode SOULBRAIN CO., LTD (KR) 2025-11-11 US disclosed
EP-4638440-A1 HETEROCYCLIC GLP-1 AGONISTS Gasherbrum Bio, Inc. (US) 2025-10-29 EP disclosed
US-20250326726-A1 FERROPTOSIS INHIBITORS-PHENOXAZINE ACETAMIDES SIRONAX BEIJING CO LTD (CN) 2025-10-23 US disclosed
US-20250250269-A1 HETEROCYCLIC GLP-1 AGONISTS GASHERBRUM BIO, INC. 2025-08-07 US disclosed
US-12378234-B2 Crystalline polymorphs of a 1-thiazol-2-yl-pyrazole-5-carboxylic acid derivative BANTAM PHARMACEUTICAL, LLC (US) 2025-08-05 US disclosed
WO-2025137483-A1 RHO-ASSOCIATED PROTEIN KINASE INHIBITORS ELI LILLY AND COMPANY (US) 2025-06-26 WO disclosed
EP-4307402-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2025-06-25 EP disclosed
EP-0982304-A1 Piperidine derivatives having effects on serotonin related systems ELI LILLY AND COMPANY (US) 2000-03-01 EP disclosed
WO-2000002859-A1 N-SUBSTITUTED NAPHTHALENE CARBOXAMIDES AS NEUROKININ-RECEPTOR ANTAGONISTS ASTRAZENECA AB (SE) 2000-01-20 WO disclosed
WO-2000000203-A1 AZEPINE DERIVATIVES HAVING EFFECTS ON SEROTONIN RELATED SYSTEMS ELI LILLY AND COMPANY (US) 2000-01-06 WO disclosed
WO-2000000198-A1 PIPERIDINE DERIVATIVES HAVING EFFECTS ON SEROTONIN RELATED SYSTEMS ELI LILLY AND COMPANY (US) 2000-01-06 WO disclosed
WO-2000000196-A1 PYRROLIDINE AND PYRROLINE DERIVATIVES HAVING EFFECTS ON SEROTONIN RELATED SYSTEMS ELI LILLY AND COMPANY (US) 2000-01-06 WO disclosed
US-5985853-A β-methoxy acrylic acid derivatives, method for preparing same, and use of said derivatives as pesticides HOECHST MARION ROUSSEL (FR) 1999-11-16 US disclosed
EP-0821688-A1 NOVEL $g(b)-METHOXY ACRYLIC ACID DERIVATIVES, METHOD FOR PREPARING SAME, AND USE OF SAID DERIVATIVES AS PESTICIDES Hoechst Schering AgrEvo S.A. (FR) 1998-02-04 EP disclosed
WO-1996032399-A1 NOVEL β-METHOXY ACRYLIC ACID DERIVATIVES, METHOD FOR PREPARING SAME, AND USE OF SAID DERIVATIVES AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 1996-10-17 WO disclosed
US-4354034-A Dihalophenoxypropionic acids and their derivatives, and their use as cotton desiccants IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-10-12 US disclosed
US-4001426-A HAVING CORONARY VASODILATOR ACTIVITY SMITHKLINE CORPORATION (US) 1977-01-04 US disclosed